Results 141 to 150 of about 10,003,521 (346)
Charting New Directions: Hogg Foundation for Mental Health
Hogg Foundation for Mental ...
Hogg Foundation for Mental Health
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Self-supervised learning strategies for jet physics
We extend the re-simulation-based self-supervised learning approach to learning representations of hadronic jets in colliders by exploiting the Markov property of the standard simulation chain.
Patrick Rieck +7 more
doaj +1 more source
Artificial intelligence can emulate human normative judgments on emotional visual scenes
Affective reactions have deep biological foundations; however, in humans, the development of emotion concepts is also shaped by language and higher-order cognition. A recent breakthrough in artificial intelligence (AI) has been the creation of multimodal
Zaira Romeo, Alberto Testolin
doaj +1 more source
Hogg Foundation News, 1995, No. 1
This issue of the newsletter from the Hogg Foundation for Mental Health contains an article with photos about the foundation's advisory council, contains an article with photos about foundation officers, and lists information about foundation ...
Hogg Foundation for Mental Health
core
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
On the Dynamic Foundation of Evolutionary Stability in Continuous Models
Oechssler J, Riedel F. On the Dynamic Foundation of Evolutionary Stability in Continuous Models. Journal of Economic Theory.
Oechssler, J. +1 more
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

