Results 281 to 290 of about 10,003,521 (346)

Plausible but Unimplantable: A Trustworthiness Audit of Shape Completion Foundation Models for Cranial Defect Reconstruction

Marek Wodziński, Kamil Kwarciak, Daria Hemmerling, Mateusz Danioł   +3 more
openalex   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Clinical artificial intelligence applications of vision-language foundation models. [PDF]

PLOS Digit Health
Thirunavukarasu AJ, Li S, Qin P, Nie D, Sanghera R, Lim E, Yu J, Zhang L.   +7 more
europepmc   +1 more source

Probing Spatial and Spectral Grounding in EEG Foundation Models

Kleanthis Avramidis, Ivan Tashev, Dimitra Emmanouilidou   +2 more
openalex   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

BrainCodes: A Lightweight EEG Foundation Model over Discrete Neural Codes

Kleanthis Avramidis, Ivan Tashev, Dimitra Emmanouilidou   +2 more
openalex   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Scaling ECG Foundation Models and Identifying a Threshold for Effective Representation Learning

Sriram R, Nenadic I, Shahrabani E, Goonewardena SN, Yao S, Farrell B, Loring Z, Murthy VL.   +7 more
europepmc   +1 more source

Bridging ancestry gaps in genomic risk prediction with tabular foundation models. [PDF]

Bioinformatics
Das A, Cui Y.
europepmc   +1 more source

How Far Can Foundation Models Be Distilled for Efficient Jet Tagging?

Jay Agarwal, Siddharth Khare, Dhruv Kumar   +2 more
openalex   +1 more source