Results 41 to 50 of about 10,003,521 (346)

Foundation models in bioinformatics

National Science Review
ABSTRACT With the adoption of foundation models (FMs), artificial intelligence (AI) has become increasingly significant in bioinformatics and has successfully addressed many historical challenges, such as pre-training frameworks, model evaluation and interpretability. FMs demonstrate notable proficiency in managing large-scale, unlabeled
Fei Guo, Renchu Guan, Yaohang Li, Qi Liu, Xiaowo Wang, Can Yang, Jianxin Wang   +6 more
openaire   +2 more sources

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

HDAC6 and TDP-43 promote autophagy impairment in amyotrophic lateral sclerosis

Neurobiology of Disease
TDP-43 is known to bind the mRNA of histone deacetylase 6 (HDAC6), influencing its RNA translation. Many studies suggest that HDAC6 participates in the regulation of autophagy, which we found impaired in sporadic amyotrophic lateral sclerosis (sALS ...
Matteo Bordoni, Eveljn Scarian, Emanuela Jacchetti, Camilla Viola, Luca Diamanti, Francesca Dragoni, Rosalinda Di Gerlando, Bartolo Rizzo, Manuela Teresa Raimondi, Stella Gagliardi, Orietta Pansarasa   +10 more
doaj   +1 more source

On a Foundation Model for Operating Systems

CoRR, 2023
Machine Learning for Systems Workshop at 37th NeurIPS Conference, 2023, New Orleans, LA ...
Divyanshu Saxena, Nihal Sharma, Donghyun Kim 0002, Rohit Dwivedula, Jiayi Chen, Chenxi Yang, Sriram Ravula, Zichao Hu, Aditya Akella, Sebastian Angel, Joydeep Biswas, Swarat Chaudhuri, Isil Dillig, Alex Dimakis, Philip Brighten Godfrey, Daehyeok Kim, Christopher J. Rossbach, Gang Wang   +17 more
openaire   +2 more sources

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Hogg Foundation News, 1988, No. 1 [PDF]

, 1988
This issue of the newsletter from the Hogg Foundation for Mental Health lists three new publications, and contains the article "A Look at Texas' Future: The Establishment of Three Mental Health Commissions" and an update on Hogg ...
Hogg Foundation for Mental Health
core  

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Hogg Foundation News, 1989, No. 2 [PDF]

, 1989
This issue of the newsletter from the Hogg Foundation for Mental Health lists three new publications for sale, has a notice about Hogg Foundation officers teaching during the spring semester, and a notice about a new study director to work on three ...
Hogg Foundation for Mental Health
core  

Can time-series foundation models perform building energy management tasks?

Data-Centric Engineering
Building energy management (BEM) tasks require processing and learning from a variety of time-series data. Existing solutions rely on bespoke task- and data-specific models to perform these tasks, limiting their broader applicability.
Ozan Baris Mulayim, Pengrui Quan, Liying Han, Xiaomin Ouyang, Dezhi Hong, Mario Bergés, Mani Srivastava   +6 more
doaj   +1 more source

Time to relect- Irish Hospice Foundation survey about death, dying and bereavement during the COVID-19 pandemic

, 2023
The Time to Reflect survey was commissioned by Irish Hospice Foundation to explore the impact of COVID-19 on the experiences and perceptions of the Irish population in relation to dying, death, and bereavement during this time.
Irish Hospice Foundation
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