Results 41 to 50 of about 25,915 (264)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Surcharge Load Effect on Additional Ground Settlement of Narrow and Elongated Foundation Pit

Chengshi guidao jiaotong yanjiu
ObjectiveIn foundation pit engineering, surcharge load acting on the perimeter of the foundation pit (hereinafter referred to as "pit perimeter") will induce additional ground settlement, which exerts a significant impact on the safety of the foundation ...
Ningjie HU, Nianwu LIU, Kai FANG
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Fluid-Solid Coupling Effect on Numerical Simulation of Deep Foundation Pit Deformation in Soft Soil Area

Applied Sciences, 2022
Groundwater is abundant in soft soil areas, which has a significant impact on the excavation deformation of foundation pits. In this paper, based on the monitoring of deep foundation pits with waterproof curtains in Shanghai deep foundation pits, COMSOL ...
Yu Zhang, Zuodong Jin, Yunlong Hou, Bingbing Han, Charles Ntakiyimana   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Cause Analysis of Seepage Disaster in Deep Foundation Pit of Metro Station in Karst Stratum

Chengshi guidao jiaotong yanjiu
Objective In-depth study should be made on the seepage stability during deep foundation pit excavation in water-rich karst stratum in consideration of the water inrush disaster at the side wall or bottom of the pit during excavation construction in water-
WANG Xiangqiu, CHEN Shichao, XIAO Yingping   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Study on Deformation Characteristics of Deep Foundation Pit Soil and Retaining Structure of Subway Station in Guangzhou Area With Composite Strata

Advances in Civil Engineering
The excavation of the deep foundation pit of subway station may cause excessive deformation of foundation pit and retaining structure and then pose a threat to the safety of surrounding buildings and people.
Wufeng Mao, Wentian Xu, Yanmei Ruan, Xinyu Tian   +3 more
doaj   +1 more source

Deformation Control for Foundation Pit Segmented Construction Adjacent to Operational High-speed Railway Lines

Chengshi guidao jiaotong yanjiu
Objective Limited land use resource and arrangement adjacent to operational high-speed railway lines pose significant challenges to some city foundation pit constructions and the railway operational safety.
LI Xiaolong, LIAO Weilian, XIAO Fei, CHEN He, DI Honggui, HE Shuqi   +5 more
doaj   +1 more source

Preliminary numerical analysis of the influence of pit-in-pit excavation on the stability of the foundation pit supported by diaphragm wall

IOP Conference Series: Earth and Environmental Science, 2020
Abstract Pit-in-pit is common in foundation pit-engineering practice. Pit-in-pit excavation disturbs the stress field in the passive zone of the foundation pit, which induces the loss of soil resistance in the passive zone and adversely affects the safety of the foundation pit.
Yong Shao, Congxin Chen, Yun Zheng, Yapeng Zhang   +3 more
openaire   +1 more source