Results 51 to 60 of about 1,969,766 (248)

Study on the Rheological Properties and Constitutive Model of Shenzhen Mucky Soft Soil [PDF]

open access: yes, 2014
In order to obtain the basic parameters of numerical analysis about the time-space effect of the deformation occurring in Shenzhen deep soft-soil foundation pit, a series of triaxial consolidated-undrained shear rheology tests on the peripheral mucky ...
Zhao, Bao-yun   +4 more
core  

Calculation of passive earth pressure for finite soil in foundation pit under pit-in-pit condition

open access: yes, 2018
© 2018, Science Press. All right reserved. Pit-in-pit usually occurs in pit engineering practices, making the soil at the bottom of the foundation pit become a limited soil. Thus, Rankine earth pressure theory based on conventional semi-infinite space is
Han, Tong Chun   +2 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Research on Influence of Deep Foundation Pit Excavation and Dewatering on Pile Foundation of Railway Bridge

open access: yes, 2021
The three-dimensional numerical model of the foundation pit engineering is established, and the fluid-structure coupling method is used to calculate the settlement of the pile foundation of the adjacent railway bridge caused by the excavation and ...
Yu Changyi, Liu Tianyun, Zhu Nan
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Study on Anti-Heave Stability and Deformation Characteristics of Narrow Foundation Pits in Ningbo Metro

open access: yesChengshi guidao jiaotong yanjiu
[Objective] Compared with wide foundation pits, the stress and displacement field changes of the soil at pit bottom and outside caused by narrow foundation pit excavation are smaller.
YAO Renxing   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Irish Hospice Foundation Annual Report 2020

open access: yes, 2021
Every death matters – and we only have one chance to get it right. Many of the experiences of dying, death and bereavement during 2020 fell very far short of the expressed wishes of the Irish people in relation to what they want for themselves or their ...
Irish Hospice Foundation
core  

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