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Founder effect: assessment of variation in genetic contributions among founders.
Human biology, 1994We present a Monte Carlo method for determining the distribution of founders' genetic contributions to descendant cohorts. The simulation of genes through known pedigrees generates the probability distributions of contributed genes in recent cohorts of descendants, their means, and their variances. Genealogical data from three populations are analyzed:
E, O'Brien +3 more
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Population Bottlenecks and Founder Effects
2006Abstract Patterns of geographic variation arise from the combined effects of migration, selection, mutation, and genetic drift. One measure of the evolutionary potential for such geographic differentiation is the level of additive genetic variance (i.e., the linear resemblance between relatives, hereafter denoted VA; see Roff, Ch.
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The founder effect in a human isolate: Evolutionary implications
American Journal of Physical Anthropology, 1970AbstractAn investigation of the founder effect has been made on the H‐leut, a religious isolate. Ninety‐one founders, representing a maximum of 150 independent genomes, have been shown to account for the total gene pool of the 9,536 people in two of the three major subpopulations within the isolate, the S‐leut and the L‐leut.
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The role of founder effects on the evolution of reproductive isolation
Journal of Evolutionary Biology, 2013AbstractSeveral theories argue that large changes in allele frequencies through genetic drift after a small founding population becomes allopatrically isolated can lead to significant changes in reproductive isolation and thus trigger the origin of new species. For this reason, founder speciation has been proposed as a potent force in the generation of
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The evolution of founder identity as an authenticity work process
Journal of Business Venturing, 2022Isobel O'Neil +2 more
exaly
Are Founder-Led Firms Less Susceptible to Managerial Myopia?
Entrepreneurship Theory and Practice, 2020Jeffrey G. Covin, Charlotte Schuster
exaly
Founder team prior work experience: An asset or a liability for startup growth?
Strategic Entrepreneurship Journal, 2022Shaker Zahra, Niron Hashai
exaly
Founder CEOs and innovation: Evidence from CEO sudden deaths in public firms
Research Policy, 2020Joon Mahn Lee
exaly

