Results 51 to 60 of about 149,498 (213)

Cultural adaptation and psychometric properties of the 8-item Patient Health Questionnaire (PHQ-8) to screen for depression in southwestern Madagascar

Cambridge Prisms: Global Mental Health
There have been no culturally validated measures to screen for depression in Madagascar. In 2022–2023, we conducted qualitative studies in the Bay of Ranobe area in southwestern Madagascar to understand local mental health syndromes specific to this ...
Hervet J. Randriamady, Manasi Sharma, Rocky E. Stroud, Aroniaina M. Falinirina, Romario, Madeleine Rasoanirina, Nadège V. Volasoa, Frédéric Déclerque, Marc Y. Solofoarimanana, Jean C. Mahefa, Hanitra O. Randriatsara, Karestan C. Koenen, Christopher D. Golden   +12 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Determination of the main factors of the gross regional product level by econometric modeling methods for the totality of regions of the Russian Federation

Статистика и экономика, 2019
The purpose of the research is to identify factors that determine the level of gross regional product, using the construction of econometric models. In terms of the economic theory the volume of gross added value of the region depends on existence of ...
Yu. S. Ivchenko
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Development and psychometric evaluation of nutrigenomics and personalized nutrition-related knowledge, attitude, and behavior questionnaire in dietetic students and professionals

Scientific Reports
This study aimed to develop and test the psychometric properties of a questionnaire assessing knowledge, attitudes, and behaviors (KAB) related to nutrigenomics and personalized nutrition (PN) in dietetic students and professionals in India. A literature
Panchali Moitra, Janvi Nemani, Saba Madre, Jagmeet Madan   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Linear perturbation renormalization group method for Ising-like spin systems

Condensed Matter Physics, 2013
The linear perturbation group transformation (LPRG) is used to study the thermodynamics of the axial next-nearest-neighbor Ising model with four spin interactions (extended ANNNI) in a field. The LPRG for weakly interacting Ising chains is presented. The
J. Sznajd
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Hyperspectral Image Super-Resolution via Wavelet Decomposition Guidance and Cross-Dimensional Feature Interaction

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Hyperspectral images aggregate abundant spectral information, but their spatial resolution is often limited due to constraints inherent in sensor design.
Pengyue Zhang, Donge Zhao, Yayun Ma, Wenbo Chu   +3 more
doaj   +1 more source