Results 61 to 70 of about 23,758,649 (247)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Estimação do volume de árvores utilizando redes neurais artificiais Estimate of tree volume using artificial neural nets

open access: yesRevista Árvore, 2009
Rede neural artificial consiste em um conjunto de unidades que contêm funções matemáticas, unidas por pesos. As redes são capazes de aprender, mediante modificação dos pesos sinápticos, e generalizar o aprendizado para outros arquivos desconhecidos.
Eric Bastos Gorgens   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Finite Difference Approximation for Linear Stochastic Partial Differential Equations with Method of Lines [PDF]

open access: yes
A stochastic partial differential equation, or SPDE, describes the dynamics of a stochastic process defined on a space-time continuum. This paper provides a new method for solving SPDEs based on the method of lines (MOL).
McDonald, Stuart
core  

Operation Four Minutes Article

open access: yes, 1982
Newspaper article focused on Operation Four Minutes, an idea that is focused on training people to have appropriate crisis response ...
Operation Four Minutes
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Antea Group Archeologie 2020/159

open access: yes, 2021
In augustus 2020 – maart 2021 heeft Antea Group een archeologisch bureauonderzoek en inventariserend veldonderzoek uitgevoerd ter voorbereiding op het verleggen van een DN400 drinkwaterleiding in Ewijk, gemeente Beuningen.
Fens, R.L. (Antea Group)   +1 more
core   +1 more source

Functional Integral Approaches to the Bosonization of Effective Multi-Quark Interactions with U_A(1) Breaking

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2006
Low energy hadron phenomenology involving the (u,d,s) quarks is often approached through effective multi-quark Lagrangians with the symmetries of QCD.
Brigitte Hiller   +3 more
doaj  

Evaluating the cross-cultural competence instrument for healthcare professionals (CCCHP) among nurses in Okinawa, Japan

open access: yesBMC Health Services Research
Background To provide better quality healthcare services to patients with different linguistic and cultural backgrounds, the cross-cultural competence of medical professionals is important.
Chieko Shirai   +2 more
doaj   +1 more source

Cultural adaptation and psychometric properties of the 8-item Patient Health Questionnaire (PHQ-8) to screen for depression in southwestern Madagascar

open access: yesCambridge Prisms: Global Mental Health
There have been no culturally validated measures to screen for depression in Madagascar. In 2022–2023, we conducted qualitative studies in the Bay of Ranobe area in southwestern Madagascar to understand local mental health syndromes specific to this ...
Hervet J. Randriamady   +12 more
doaj   +1 more source

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