Results 71 to 80 of about 879,900 (242)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Finite Approximations to Quantum Physics: Quantum Points and their Bundles

, 1993
There exists a physically well motivated method for approximating manifolds by certain topological spaces with a finite or a countable set of points.
A.P. Balachandran, Aleksandrov, Aneziris, Avron, Balachandran, Balachandran, Bamonte, Bombelli, Creutz, de Gennes, Drouffe, E. Ercolessi, G. Bimonte, Hilton, Hooft, Ivashchenko, Jaffe, Kleinert, Kogut, McCoy, Munkres, P. Teotonio-Sobrinho, Parisi, Rabin, Sorkin, Sorkin, Stanley, Van Dyck   +27 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Functional Integral Approaches to the Bosonization of Effective Multi-Quark Interactions with U_A(1) Breaking

Symmetry, Integrability and Geometry: Methods and Applications, 2006
Low energy hadron phenomenology involving the (u,d,s) quarks is often approached through effective multi-quark Lagrangians with the symmetries of QCD.
Brigitte Hiller, Alexander A. Osipov, Véronique Bernard, Alex H. Blin   +3 more
doaj  

Evaluating the cross-cultural competence instrument for healthcare professionals (CCCHP) among nurses in Okinawa, Japan

BMC Health Services Research
Background To provide better quality healthcare services to patients with different linguistic and cultural backgrounds, the cross-cultural competence of medical professionals is important.
Chieko Shirai, Daisuke Nonaka, Jun Kobayashi   +2 more
doaj   +1 more source

Cultural adaptation and psychometric properties of the 8-item Patient Health Questionnaire (PHQ-8) to screen for depression in southwestern Madagascar

Cambridge Prisms: Global Mental Health
There have been no culturally validated measures to screen for depression in Madagascar. In 2022–2023, we conducted qualitative studies in the Bay of Ranobe area in southwestern Madagascar to understand local mental health syndromes specific to this ...
Hervet J. Randriamady, Manasi Sharma, Rocky E. Stroud, Aroniaina M. Falinirina, Romario, Madeleine Rasoanirina, Nadège V. Volasoa, Frédéric Déclerque, Marc Y. Solofoarimanana, Jean C. Mahefa, Hanitra O. Randriatsara, Karestan C. Koenen, Christopher D. Golden   +12 more
doaj   +1 more source

Efficient computation of high index Sturm-Liouville eigenvalues for problems in physics

, 2008
Finding the eigenvalues of a Sturm-Liouville problem can be a computationally challenging task, especially when a large set of eigenvalues is computed, or just when particularly large eigenvalues are sought.
Andrew, Andrew, Andrew, Bailey, Bailey, Canosa, Coffey, Degani, G. Vanden Berghe, Gelfand, Gordon, Hairer, Iserles, Iserles, Iserles, Iserles, Iserles, Iserles, Ixaru, Ixaru, Ixaru, Ixaru, Ixaru, Ixaru, Ixaru, Ixaru, Ledoux, Ledoux, Ledoux, Ledoux, Ledoux, M. Van Daele, Magnus, Marletta, Moan, Paine, Paine, Pruess, Pruess, Pruess, Pryce, Pryce, Smooke, Strang, V. Ledoux, Vanden Berghe, Vanden Berghe, Zettl   +47 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Determination of the main factors of the gross regional product level by econometric modeling methods for the totality of regions of the Russian Federation

Статистика и экономика, 2019
The purpose of the research is to identify factors that determine the level of gross regional product, using the construction of econometric models. In terms of the economic theory the volume of gross added value of the region depends on existence of ...
Yu. S. Ivchenko
doaj   +1 more source

Parquet solution for a flat Fermi surface

, 1996
We study instabilities occurring in the electron system whose Fermi surface has flat regions on its opposite sides. Such a Fermi surface resembles Fermi surfaces of some high-$T_c$ superconductors.
A. A. Abrikosov, A. A. Abrikosov, A. A. Nersesyan, A. H. Castro Neto, A. H. Castro Neto, A. H. Castro Neto, A. Houghton, A. Houghton, A. Houghton, A. Luther, A. Luther, A. Virosztek, Anatoley T. Zheleznyak, B. G. Levi, B. Halperin, B. Roulet, C. N. Yang, D. C. Mattis, D. J. Scalapino, D. J. Scalapino, D. S. Dessau, D. V. Khveshchenko, D. V. Khveshchenko, D. V. Khveshchenko, D. V. Khveshchenko, D. V. Khveshchenko, E. M. Lifshitz, F. D. M. Haldane, F. D. M. Haldane, G. Kotliar, G. T. Zimanyi, H. J. Schulz, H. J. Schulz, H.-J. Kwon, H.-J. Kwon, I. Affleck, I. E. Dzyaloshinskii, I. E. Dzyaloshinskii, I. E. Dzyaloshinskii, I. E. Dzyaloshinskii, I. E. Dzyaloshinskii, I. E. Dzyaloshinskii, I. E. Dzyaloshinskii, I. T. Diatlov, Igor E. Dzyaloshinskii, J. Ruvalds, J. Solyom, L. P. Gor'kov, M. Pernici, P. A. Lee, P. B. Wiegmann, P. Kopietz, P. Kopietz, P. Kopietz, P. Nozières, P. W. Anderson, R. A. Klemm, R. Hlubina, R. Shankar, S. A. Brazovskii, S. A. Brazovskii, S. A. Brazovskii, V. M. Yakovenko, V. M. Yakovenko, V. M. Yakovenko, V. N. Prigodin, V. V. Sudakov, Victor M. Yakovenko, Y. A. Bychkov, Y. M. Li, Yu. A. Firsov, Z.-X. Shen   +71 more
core   +1 more source