Results 81 to 90 of about 206 (201)

Antiseizure potency and neurotoxicity of the enantiomers of fenfluramine and norfenfluramine in rats and correlations with their concentrations in plasma and brain

Epilepsia, EarlyView.
Abstract Objective Based on the evidence that fenfluramine‐induced anorexia, weight loss, and cardiovascular toxicity are primarily mediated by the d‐enantiomers of fenfluramine and its metabolite norfenfluramine, we investigated pharmacokinetic/pharmacodynamic correlations for the active enantiomers of fenfluramine and norfenfluramine in the rat ...
Yara Sheeni, Dinorah Barasch, Tawfeeq Shekh‐Ahmad, Emilio Perucca, Meir Bialer   +4 more
wiley   +1 more source

Hybrid Inverters With Dual Switching Frequencies for Switched Reluctance Motors

Energy Science &Engineering, EarlyView.
A hybrid dual‐switching‐frequency inverter for SRMs is proposed, combining SiC and IGBT devices based on rotor inductance. The method enables accurate current tracking with simple hysteresis control, significantly reducing torque ripple, vibration, and acoustic noise while cutting inverter cost compared to full‐SiC solutions.
Fares S. El‐Faouri, Majd G. Batarseh, Hamzeh J. Jaber, Ayman Faza, Wejdan Abu Elhaija   +4 more
wiley   +1 more source

Materials and Music: Selective Imperfection as a Generative Framework for Analysis, Creativity and Discovery

Interdisciplinary Materials, EarlyView.
Vibrations in matter, from spider webs to molecules, water to flames, share a grammar with music. We propose that creativity emerges when constraints force expansion beyond existing possibilities. Selective imperfection restores balance, enabling invention.
Markus J. Buehler
wiley   +1 more source

Spatiotemporal dynamics of brain function network during proprioception rehabilitation after anterior cruciate ligament reconstruction: A randomized trial

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
The improvement of proprioceptive function after ACLR is related to the optimization of spatiotemporal dynamics of SM, CC, DM, CB and VI functional networks. Rehabilitation optimization can incorporate visual–cognitive dual‐task exercises. Abstract Purpose In this study, we aimed to examine the dynamic functional network connectivity (dFNC) patterns ...
Xiaoyun Zhuang, Chunmei Sui, Xuesong Han, Xiaoying Liu, Xiaoyang Wang, Xiumei Zhu, Ming Xu, Yin Qin   +7 more
wiley   +1 more source

Mathematical Vector Quantity Modulated Three Phase Four Leg Inverter

, 2016
In this paper it has been shown that any unbalanced and distorted three-phase currents can be efficiently generated as output from a four-leg (4L) inverter with mathematical implementation of three dimensional (3D) space vector pulse width modulation (SVPWM) in \( \upalpha{ - }\upbeta{ - }\upgamma \) frame.
Bhaskar Bhattacharya, Ajoy Kumar Chakraborty   +1 more
openaire   +1 more source

NKX2‐1 Downstream Regulatory Structural Variants Explain a Substantial Proportion of Molecular Diagnoses in Patients With Benign Hereditary Chorea

Movement Disorders, EarlyView.
Abstract Background NKX2‐1–related disorders (NKX2‐1‐RDs) classically present with a triad of neurological, endocrine, and pulmonary manifestations, including benign hereditary chorea. However, in a fraction of patients, NKX2‐1 coding variants are not detected, and variants outside the NKX2‐1 locus have been reported.
Robin Wijngaard, Lucy Dougherty‐de Miguel, German Demidov, Galuh Astuti, Amaia Lasa‐Aranzasti, Ana Cueto‐González, Marta Correa‐Vela, Carlos Lázaro‐Hernández, Charlotte A. Haaxma, Clara D.M. van Karnebeek, David Gómez‐Andrés, Ignacio Iglesias‐Serrano, Jiddeke M. van de Kamp, Jolanda Schieving, Laura Trujillano, Marc Engelen, Beatriz Muñoz‐Cabello, Roderick P.P.W.M. Maas, Thatjana Gardeitchik, Victoria Gonzalez, Annemarie de Vreugd, Cristina Pérez‐Sanchez, Elisabet Lloveras, Erik‐Jan Kamsteeg, Maartje Pennings, Natalia Rey‐Viñets, Javier Sánchez, Ronald van Beek, Antonio Moreno‐Galdó, Lisenka E.L.M. Vissers, Kornelia Neveling, Anna Marcé‐Grau, Machteld M. Oud, Belén Pérez‐Dueñas   +33 more
wiley   +1 more source

Quantifying Skin Sodium Concentration With Novel Very Rapid Biexponential T2 Relaxometry and Signal Loss Compensation Methodology

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To accurately measure skin tissue sodium concentration (TSC) through development of spin‐3/2 relaxometry methodology that also considers blood sodium. Methods Mxy generation during RF excitation is substantially reduced by very rapid T2f.
Gurparkash Singh, Christian Beaulieu, Rob Stobbe   +2 more
wiley   +1 more source

A Case of Distal Hereditary Motor Neuronopathy‐7 With Two Novel VWA1 Variants in Compound Heterozygosity

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Distal hereditary motor neuronopathy‐7 (HMNR7) is an autosomal recessive VWA1‐related disorder characterized predominantly by distal motor involvement. A 41‐year‐old man with a history of childhood orthopedic surgery for foot deformities exhibited progressive distal weakness and muscle atrophy with lower limb predominance. Electrophysiological
Toshiyuki Kakumoto, Kenta Orimo, Takashi Matsukawa, Jun Mitsui, Shoji Tsuji   +4 more
wiley   +1 more source

Hexapod Locomotion Across Structured and Unstructured Terrains: A Data‐Driven Review of Modeling, Control, and Validation

Journal of Field Robotics, EarlyView.
ABSTRACT The design of a hexapod is complex and requires integration between kinematic models, control systems, and sensing. Existing literature has reviewed these sub‐systems in isolation. Since 2021, there has been no review of the field despite significant advancements in soft soil, lunar traversal, and artificial intelligence.
Akhil Rampersad, Bashan Naidoo
wiley   +1 more source

Probing the Energy Trilemma Pillars: Do Innovation Pathways Deliver Cleaner and More Equitable Energy Systems?

Sustainable Development, EarlyView.
ABSTRACT Balancing reliable energy supply, equitable access, and environmental sustainability is a central challenge of the global energy transition. This study examines how innovation influences the energy trilemma by shaping energy security, energy equity, and environmental sustainability across 115 countries from 2011 to 2023.
Kingsley Imandojemu, Omozele Lynda Showunmi, Felix Orole, Damilola Felix Eluyela, Hammed Oluwaseyi Musibau, Romanus Osabohien   +5 more
wiley   +1 more source