Results 91 to 100 of about 894 (259)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Social Media and Its Role in Knowledge Exchange between Digital Preservation Experts based on Honeycomb Model [PDF]
بازیابی دانش و نظامهای معنایی, 2015 Purpose: This study aims to identify the social media and their role in knowledge exchange between digital preservation experts based on the Honeycomb model for sharing scientific contents.
Mitra samiei
doaj
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
A conexão entre lugares e espaços proporcionada pela a rede Foursquare
Intexto, 2011 Com o desenvolvimento de aparatos de comunicação móvel como smartphones, celulares, tablets e laptops a contextualização dos espaços físicos nas cidades pode estar agora conectado ao conteúdo na internet. Um dos expoentes mais claros desta convergência
Eduardo Campos Pellanda
doaj
Exploring Transformer and Graph Convolutional Networks for Human Mobility Modeling. [PDF]
Sensors (Basel), 2023 Corrias R, Gjoreski M, Langheinrich M.
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Temporal visitation patterns of points of interest in cities on a planetary scale: a network science and machine learning approach. [PDF]
Sci Rep, 2023 Betancourt F, Riascos AP, Mateos JL.
europepmc +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
User Re-Identification via Confusion of the Contrastive Distillation Network and Attention Mechanism. [PDF]
Sensors (Basel), 2023 Zhang M +5 more
europepmc +1 more source