Results 81 to 90 of about 20,673 (286)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Individualized vs. Generalized Assessments: Why RLUIPA Should Not Apply to Every Land-Use Request [PDF]
, 2012 Courts and advocates alike have struggled to articulate a coherent rule regarding when the Religious Land Use and Institutionalized Persons Act (RLUIPA) should apply to local governments\u27 land-use decisions. When it is applied too broadly, RLUIPA runs
Ertmer, Katie M.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
, 2014 Food and drink are two of the most basic needs of human beings. However, as society evolved, food and drink became also a strong cultural aspect, being able to describe strong differences among people.
Almeida, Jussara +4 more
core +1 more source
Link prediction in Foursquare network
, 2016 Foursquare is an online social network and can be represented with a bipartite network of users and venues. A user-venue pair is connected if a user has checked-in at that venue. In the case of Foursquare, network analysis techniques can be used to enhance the user experience.
Fortuna, Rok, Marovt, Urban
openaire +2 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Structural Mechanics of Engineering Constructions and Buildings, 2016 In this paper, based on the Foursquare element sampling algorithm is presented finite element calculation of shells of revolution considering transverse shear strains in different variants of the reference tilt angle of the normal process of ...
Yu V Klochkov +2 more
doaj
Museo y comunicación 2.0. Situación en España
Documentación de las Ciencias de la Información, 2017 Se analiza cómo la difusión de los museos españoles ha evolucionado con la aparición de las tecnologías de la comunicación y la información (TICs), generando nuevos vínculos comunicativos y situando al visitante en el eje central de los mismos. Se valora
Luis Jesús Jiménez-Orellana
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source