Results 71 to 80 of about 894 (259)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

FINITE ELEMENT ANALYSIS 0F STRESS-STRAIN STATE OF SHELLS OF REVOLUTION WITH TAKING INTO ACCOUNT THE STRAIN OF TRANSVERSAL SHEARING

Structural Mechanics of Engineering Constructions and Buildings, 2016
In this paper, based on the Foursquare element sampling algorithm is presented finite element calculation of shells of revolution considering transverse shear strains in different variants of the reference tilt angle of the normal process of ...
Yu V Klochkov, A P Nikolaev, T R Ischanov   +2 more
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Point of Interest Recommendation System Using Sentiment Analysis

Journal of Information Science Theory and Practice
Sentiment analysis is one of the promising approaches for developing a point of interest (POI) recommendation system. It uses natural language processing techniques that deploy expert insights from user-generated content such as reviews and feedback.
Gaurav Meena, Ajay Indian, Krishna Kumar Mohbey, Kunal Jangid   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Museo y comunicación 2.0. Situación en España

Documentación de las Ciencias de la Información, 2017
Se analiza cómo la difusión de los museos españoles ha evolucionado con la aparición de las tecnologías de la comunicación y la información (TICs), generando nuevos vínculos comunicativos y situando al visitante en el eje central de los mismos. Se valora
Luis Jesús Jiménez-Orellana
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

ASTHN: Adaptive Spatio-Temporal Hypergraph Network for Next POI Recommendation

ISPRS International Journal of Geo-Information
The widespread use of mobile Internet- and location-based services has generated large-scale check-in data in location-based social networks, creating opportunities for intelligent urban-mobility analysis and personalized mobility services.
Fang Liu, Tianrui Li, Jiangtao Li
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Contextualized Relevance Evaluation of Geographic Information for Mobile Users in Location-Based Social Networks

ISPRS International Journal of Geo-Information, 2015
The relevance of geographic information to mobile users must be evaluated by taking into account the usage context. This paper assumes that emerging Location-based Social Networks (LBSNs) contain contextual information rich enough to be used in order to ...
Ming Li, Yeran Sun, Hongchao Fan
doaj   +1 more source