Results 71 to 80 of about 10,905,906 (292)
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
On a fourth order superlinear elliptic problem
Electronic Journal of Differential Equations, 2001 We prove the existence of a nonzero solution for the fourth order elliptic equation $$Delta^2u= mu u +a(x)g(u)$$ with boundary conditions $u=Delta u=0$. Here, $mu$ is a real parameter, $g$ is superlinear both at zero and infinity and $a(x)$ changes sign ...
M. Ramos, P. Rodrigues
doaj
Analytical and Solutions of Fourth Order Difference Equations
Communications in Advanced Mathematical Sciences, 2019 In this article, we presented the solutions of the following recursive sequences\[ x_{n+1}=\frac{x_{n-2}x_{n-3}}{x_{n}(\pm1\pm x_{n-2}x_{n-3})}, \] where the initial conditions $x_{-3}\ ,x_{-2}\ ,x_{-1}$\ and $x_{0}\ $are arbitrary real numbers. Also, we
Elsayed M. Elsayed, Marwa M. Alzubaidi
doaj +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Nonlinear fourth order problems with asymptotically linear nonlinearities [PDF]
Mathematica BohemicaWe investigate some nonlinear elliptic problems of the form \Delta^2v + \sigma(x) v= h(x,v)\quadin \Omega,\quad v=\Delta v=0 \quadon \partial\Omega, \eqno({\rm P}) where $\Omega$ is a regular bounded domain in $\mathbb{R}^N$, $N\geq2$, $\sigma(x ...
Abir Amor Ben Ali, Makkia Dammak
doaj +1 more source
Oscillation of fourth-order quasilinear differential equations [PDF]
, 2015 summary:We study oscillatory behavior of a class of fourth-order quasilinear differential equations without imposing restrictive conditions on the deviated argument.
Zhang, Chenghui +2 more
core +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Nonlinear singular Navier problem of fourth order
Electronic Journal of Differential Equations, 2003 We present an existence result for a nonlinear singular differential equation of fourth order with Navier boundary conditions. Under appropriate conditions on the nonlinearity $f(t,x,y)$, we prove that the problem $$displaylines{ L^{2}u=L(Lu) =f(.,u,Lu ...
Syrine Masmoudi, Malek Zribi
doaj
Hyperbolic Relaxation of a Fourth Order Evolution Equation
Abstract and Applied Analysis, 2013 We propose a hyperbolic relaxation of a fourth order evolution equation, with an inertial term , where . We prove the existence of several absorbing sets having different regularities and the existence of a global attractor that is bounded in .
Renato Colucci, Gerardo R. Chacón
doaj +1 more source
Oscillation criteria for fourth order half-linear differential equations [PDF]
, 2011 summary:Criteria for oscillatory behavior of solutions of fourth order half-linear differential equations of the form \begin{equation*} \big (|y^{\prime \prime }|^\alpha {\rm sgn\ } y^{\prime \prime }\big )^{\prime \prime } + q(t)|y|^\alpha {\rm sgn}\ y =
Jaroš, Jaroslav +4 more
core +1 more source