Results 61 to 70 of about 10,905,906 (292)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Institutions as Objects in Fourth Order Design

open access: yesShe Ji: The Journal of Design, Economics and Innovation
Fourth order design, which involves systems and environments, is a frequently misunderstood area of design. The concept of institution offers a way to clarify and enrich fourth order design in both theory and practice.
Kipum Lee
doaj   +1 more source

Riccati Technique and Asymptotic Behavior of Fourth-Order Advanced Differential Equations

open access: yesMathematics, 2020
In this paper, we deal with the oscillation of fourth-order nonlinear advanced differential equations of the form r t y ‴ t α ′ + p t f y ‴ t + q t g y σ t = 0 .
Omar Bazighifan, Ioannis Dassios
doaj   +1 more source

Nonlinear Differential Equations with Distributed Delay: Some New Oscillatory Solutions

open access: yesMathematics, 2022
The oscillation of a class of fourth-order nonlinear damped delay differential equations with distributed deviating arguments is the subject of this research.
Barakah Almarri   +3 more
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Oscillation criteria for certain nonlinear fourth order equations

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1983
This work investigates the behavior of solutions of certain nonlinear fourth order differential equations. An example is given showing that these equations can have both oscillatory and nonoscillatory solutions simultaneously.
W. E. Taylor
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

Functional Model of Dissipative Fourth Order Differential Operators

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2013
In this paper, maximal dissipative fourth order operators with equal deficiency indices are investigated. We construct a self adjoint dilation of such operators.
Tuna Hüseyin
doaj   +1 more source

Computational Bifurcations Occurring on Red Fixed Components in the λ-Parameter Plane for a Family of Optimal Fourth-Order Multiple-Root Finders under the Möbius Conjugacy Map

open access: yesMathematics, 2020
Optimal fourth-order multiple-root finders with parameter λ were conjugated via the Möbius map applied to a simple polynomial function. The long-term dynamics of these conjugated maps in the λ -parameter plane was analyzed to discover some ...
Young Hee Geum, Young Ik Kim
doaj   +1 more source

Jumping nonlinearities for fourth order B.V.P. [PDF]

open access: yesAnnales de la Faculté des sciences de Toulouse : Mathématiques, 1993
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
García-Huidobro, Marta   +1 more
openaire   +1 more source

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