Results 51 to 60 of about 4,114,452 (292)

A fourth‐order incremental ADC in three‐step

open access: yesThe Journal of Engineering, 2021
This letter presents a second‐order incremental ADC (IADC) operated in three steps, which extends the performance of a second‐order IADC close to that of a fourth‐order IADC with only two amplifiers.
Jia‐Sheng Huang   +5 more
doaj   +1 more source

Fourth-order Schr\"odinger type operator with singular potentials

open access: yes, 2016
In this paper we study the biharmonic operator perturbed by an inverse fourth-order potential. In particular, we consider the operator $A=\Delta^2-V=\Delta^2-c|x|^{-4}$ where $c$ is any constant such that ...
Gregorio, Federica, Mildner, Sebastian
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Isoperimetric inequalities of the fourth order Neumann eigenvalues

open access: yesJournal of Inequalities and Applications, 2020
In this paper, we obtain some isoperimetric inequalities for the first ( n − 1 ) $(n-1)$ eigenvalues of the fourth order Neumann Laplacian on bounded domains in an n-dimensional Euclidean space. Our result supports strongly the conjecture of Chasman.
Yanlin Deng, Feng Du
doaj   +1 more source

Fourth order gravity and experimental constraints on Eddington parameters

open access: yes, 2006
PPN-limit of higher order theories of gravity represents a still controversial matter of debate and no definitive answer has been provided, up to now, about this issue. By exploiting the analogy between scalar-tensor and fourth-order theories of gravity,
Capozziello, S., Stabile, A., Troisi, A.
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Envelope instability and the fourth order resonance

open access: yesPhysical Review Special Topics. Accelerators and Beams, 2014
The well-known envelope instability or the second order even collective mode [I. Hofmann, Phys. Rev. E 57, 4 (1998)] and the fourth order resonance 4σ=360° due to the nonlinear space charge effect in high intensity beams have been studied previously.
Chao Li, Ya Liang Zhao
doaj   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

THIRD-ORDER EFFICIENCY IMPLIES FOURTH-ORDER EFFICIENCY

open access: yesJOURNAL OF THE JAPAN STATISTICAL SOCIETY, 1996
Summary: \textit{K. Takeuchi} [Asymptotic theory of statistical inference. (1974)], \textit{K. Takeuchi} and \textit{M. Akahira} [Lect. Notes Math. 550, 604-638 (1976; Zbl 0398.62027)] and \textit{J. Pfanzagl} [Contributions to Statistics, Jaroslav Hajek Mem.
openaire   +3 more sources

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