Results 201 to 210 of about 74,948 (336)

Transcriptome Differentiation of Wild and Hatchery‐Reared Gibelion catla Fish in Bangladesh

Aquaculture, Fish and Fisheries, Volume 6, Issue 1, February 2026.
ABSTRACT Transcriptome differences between wild and hatchery‐reared Gibelion catla collected from Halda (HL) and Padma River (PD) as wild and a hatchery (HR) population in Bangladesh were identified in this study. A total of 6780 differentially expressed genes (DEGs) in HL compared to HR indicated significant variations in gene expression consistent ...
Shumaya Shafrin, Md. Alamgir Kabir, Md. Golam Rabbane   +2 more
wiley   +1 more source

Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response [PDF]

, 2012
Jaya Sangodkar, Neil S. Dhawan, Heather Melville, Varan Singh, Rui Yuan, Huma Q. Rana, Sudeh Izadmehr, Caroline Farrington, Sahar Mazhar, Suzanna Katz, Tara Albano, Pearlann Arnovitz, Rachel A. Okrent, Michael Ohlmeyer, Matthew D. Galsky, David Burstein, David Zhang, Katerina Politi, Analisa DiFeo, Goutham Narla   +19 more
openalex   +1 more source

Analyses of plasma multi‐omic data across ancestries identify novel pathways implicated in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Few genetic studies on Alzheimer's disease (AD) have incorporated multiple ancestries and omic datasets to pinpoint actionable AD risk effectors for each ancestry. METHODS Here, we first performed genetic colocalization between molecular phenotypes (proteomics and metabolomics) from two ancestral groups (European [EUR] and African
Chengran Yang, Jigyasha Timsina, Menghan Liu, John Budde, Pat Kohlfeld, William Brock, John C. Morris, David M. Holtzman, Yun Ju Sung, Carlos Cruchaga   +9 more
wiley   +1 more source

C Terminus of Hsc70-interacting Protein Promotes Smooth Muscle Cell Proliferation and Survival through Ubiquitin-mediated Degradation of FoxO1 [PDF]

, 2009
Fang Li, Ping Xie, Yongna Fan, Hua Zhang, Lianfang Zheng, Dongfeng Gu, Cam Patterson, Hui‐Hua Li   +7 more
openalex   +1 more source

The Role of Immune Infiltration and Oxidative Stress in the Progression of Cerebral Cavernous Malformation

Brain and Behavior, Volume 16, Issue 2, February 2026.
Mechanism of rupture hemorrhage in cerebral cavernous malformations. Environmental and immune factors promote the progression of lesions and induce the risk of abnormal formation or rupture of cerebrovascular vessels. Abstract Purpose of Review To review how the immune microenvironment and oxidative stress modulate the initiation, maturation, and ...
Xuesai Zhu, Yizhi Yao, Tengbo Yu, Xiao Xiao   +3 more
wiley   +1 more source

Arginase 2 Promotes Colorectal Cancer Metastasis via PI3K/AKT Pathway Activation and Regulates Tumor Immune Infiltration

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Colorectal cancer (CRC) is a leading cause of cancer‐related deaths, with metabolic reprogramming involved in its pathogenesis. Aberrant Arginase 2 (ARG2) expression is linked to malignant progression, but its role in CRC remains unclear. Methods ARG2 expression in CRC and adjacent tissues was analyzed.
Yueyan Zhang, Ning Qu, Jiale Mei, Caixia Mo, Luojuan Wei, Haixian Shen, Shanfei Zhou, Jinmin Hu, Wenqi Luo, Xianwei Mo   +9 more
wiley   +1 more source

ACE Loss Drives Renal Cell Carcinoma Growth and Invasion by Modulating AKT-FOXO1

Biologics: Targets & Therapy
Lei Yin,1– 3,* Lixin Mao,4,* Rui Yin,5,* Chengxun Lv,1,* Xiaokai Shi,4 Chuang Yue,4 Yin Chen,4 Chao Lu,4 Zonglin Wu,1 Kai Xu,4 Wei Cao4 1Department of Urology, Shidong Hospital, Yangpu District, Shidong Hospital Affiliated to University ...
Yin L, Mao L, Yin R, Lv C, Shi X, Yue C, Chen Y, Lu C, Wu Z, Xu K, Cao W   +10 more
doaj  

AKT/mTORC2 Inhibition Activates FOXO1 Function in CLL Cells Reducing B-Cell Receptor-Mediated Survival

, 2018
Emilio Cosimo, Anuradha Tarafdar, Michael W. Moles, Ailsa K. Holroyd, Natasha Malik, Mark Catherwood, Jodie Hay, Karen Dunn, Alan M. Macdonald, Sylvie M. Guichard, Declan O’Rourke, Michael T. Leach, Owen J. Sansom, Sabina Cosulich, Alison M. McCaig, Alison M. Michie   +15 more
openalex   +2 more sources

New Insights on Heat Shock Proteins as Regulators of Reactive Oxygen Species Across Various Stressors in Diseases

Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.
ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar, Triveni Kodi, Adarsh Gopinathan, Bharath Harohalli Byregowda, Krishnadas Nandakumar, Anoop Kishore   +5 more
wiley   +1 more source

Molecular Mechanisms and Therapeutic Potential of DJ‐1 in Skeletal Muscle Homeostasis and Disease

Comprehensive Physiology, Volume 16, Issue 1, February 2026.
DJ‐1 protein functions as a redox‐sensing guardian in skeletal muscle by coordinating antioxidant defense, mitochondrial homeostasis, metabolic adaptation, and anti‐atrophy signaling. Enhancing its function holds promise as a potential therapeutic strategy for muscle atrophy, ALS, and metabolic myopathies.
Yue Zhang, Menghuan Li, Xiaojing Xie, Baokai Tian, Zhenwei Bao, Xuejie Yi   +5 more
wiley   +1 more source