Results 231 to 240 of about 74,948 (336)

State‐of‐the‐Art Strategies for Circular RNA in Cancers: Opportunity and Challenge

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Overview of circular RNA in tumors. ABSTRACT Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving from once‐overlooked transcriptional byproducts to pivotal molecular regulators.
Zehao Ding   +6 more
wiley   +1 more source

Autophagy, FOXO1 and proteostasis

open access: yes, 2012
Cellen maken niet alleen voortdurend nieuwe eiwitten en bouwen steeds nieuwe structuren, maar moeten ook steeds delen kunnen afbreken, recyclen en afvoeren. Autofagie is een mechanisme dat cellen in staat stelt om onbruikbare of beschadigde cellulaire componenten af te breken.
openaire   +1 more source

Effect of Denervation on Skeletal Muscle Mitochondria in Heterozygous mtDNA Mutator Mice

open access: yesFASEB BioAdvances, Volume 8, Issue 2, February 2026.
Denervation induces mitochondrial dysfunction and oxidative stress in skeletal muscle. In PolG(+/mut) mice, denervation led to reduced mitochondrial DNA copy number and a pronounced upregulation of the antioxidant enzyme catalase, despite comparable levels of muscle atrophy, mitochondrial content, and mitochondrial dynamics‐related proteins compared to
Takanaga Shirai   +6 more
wiley   +1 more source

Supplementary Materials and Methods from PLK1 Phosphorylates PAX3-FOXO1, the Inhibition of Which Triggers Regression of Alveolar Rhabdomyosarcoma [PDF]

open access: gold, 2023
Verena Thalhammer   +11 more
openalex   +1 more source

FIGURE 4 from Piperacetazine Directly Binds to the PAX3::FOXO1 Fusion Protein and Inhibits Its Transcriptional Activity

open access: gold, 2023
Kay Nakazawa   +14 more
openalex   +1 more source

Genomic Profiling of Pediatric Solid Tumors With a Dual DNA/RNA Panel: JCCG‐TOP2 Study

open access: yesCancer Science, Volume 117, Issue 2, Page 522-535, February 2026.
In the JCCG‐TOP2 nationwide pediatric cancer genomic profiling study, 204 patients' tumors and peripheral blood from 50 institutions across Japan were successfully analyzed using a dual DNA/RNA panel. A total of 147 (72%) had potentially actionable findings, including diagnostic, prognostic, and therapeutic findings in 111 (54%), 61 (30%), and 64 (31%),
Kayoko Tao   +38 more
wiley   +1 more source

Fertility preservation in women with ovarian cancer: Finding new pathways: A case-control study

open access: yesInternational Journal of Reproductive BioMedicine, 2021
Ali Khodadadian   +8 more
doaj   +1 more source

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