Results 311 to 320 of about 199,492 (387)

Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity

Proceedings of the National Academy of Sciences of the United States of America, 2017
D. Zemmour, Alvin Pratama, S. Loughhead, D. Mathis, C. Benoist   +4 more
semanticscholar   +1 more source

The Impact of Metabolic Syndrome on Immune Regulation (IL-17, IL-23, and FOXP3+), Psoriasis Severity, Flare Frequency, and Quality of Life in Psoriasis Patients: A Cross-Sectional Study. [PDF]

Int J Inflam
Prakoeswa FRS, Maharani F, Hidayat S, Sari WA, Oktavriana T, Prakoeswa CRS, Umborowati MA, Pramuningtyas R, Bestari RS, Aisyah R, Risanti ED, Dewi LM, Anam IHM.   +12 more
europepmc   +1 more source

Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine

Macromolecular Bioscience, EarlyView.
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro, Arwa Daghrery, Caroline Anselmi, Igor Paulino M. Soares, Alexandre Henrique dos Reis‐Prado, Pedro Henrique Chaves de Oliveira, Marco C. Bottino   +6 more
wiley   +1 more source

[Pirfenidone inhibits bladder cancer xenograft growth in mice by regulating regulatory T cells]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhang H, Yan M, Zhang J, Sun P, Wang R, Guo Y.   +5 more
europepmc   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Navigating the manufacturing, testing and regulatory complexities of regulatory T cells for adoptive cell therapy. [PDF]

Front Immunol
Pikor LA, Arivazhagan S, Mendicino M, Sathiamoorthy S.   +3 more
europepmc   +1 more source

The importance of tumor microenvironment modulations in the progression of pancreatic intraductal papillary mucinous neoplasms†

The Journal of Pathology, EarlyView.
Abstract Intraductal papillary mucinous neoplasms (IPMNs) of the pancreas have attracted substantial attention since they represent the most prevalent macroscopic precursor of pancreatic cancer. Most lesions show an epithelium with low‐grade dysplasia and will remain indolent and unknown to the patient.
Antonio Pea, Claudio Luchini
wiley   +1 more source

Targeting Recipient Dendritic Cells with Sialic Acid-Modified Donor Alloantigen Prolongs Skin Transplant Survival. [PDF]

Int J Mol Sci
Sen M, Peng Q, Ratnasothy K, Ambrosini M, Kalay H, Bazoer J, Adams KE, Ouazzani NE, Ababou A, Guiliano DB, Saldaña JI, Kooyk YV, Lombardi G, Smyth LA.   +13 more
europepmc   +1 more source

Moving From Point‐Based Analysis to Systems‐Based Modeling: Knowledge Integration to Address Antimicrobial Resistance

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Optimizing antibiotic therapy requires a holistic bench‐to‐bedside approach with interdisciplinary collaboration between pharmacologists, clinicians, microbiologists, and computational scientists. Novel experimental models provide insights into drug‐pathogen interactions within complex host environments, while multiomics data provide details ...
Bhavatharini Arun, Gauri G. Rao
wiley   +1 more source

Involvement of the Programmed Death 1/Programmed Death Ligand 1 Pathway in the Immune Microenvironment of Chronic Periapical Lesions. [PDF]

Int Dent J
Song Y, Park S, Jin H, Hyun B, Oh KY.
europepmc   +1 more source