Results 321 to 330 of about 199,492 (387)

Targeted Intracellular Copper Reservoir Enhances Liver Cancer Immunotherapy

open access: yesSmall, EarlyView.
Sono‐activatable TPEN‐encapsulated cancer‐targeted nanoparticles (STCNs) with sonodynamic therapy (SDT)‐amplified immunotherapeutic properties for liver cancer treatment via endogenous cuproptosis are developed. STCNs can effectively treat liver cancer through endogenous cuproptosis by TPEN and ROS generated by SDT, resulting in increased immune ...
Tianao Xie   +15 more
wiley   +1 more source

Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch   +1 more
wiley   +1 more source

A Role for Regulatory T Cells in Cutaneous T-Cell Lymphoma; Induction of a CD4+CD25+Foxp3+ T-Cell Phenotype Associated with HTLV-1 Infection

open access: bronze, 2006
Patrick Walsh   +5 more
openalex   +1 more source

The regulatory effects and applications of TIGIT/CD155 on the tumor microenvironment in HCC

open access: yesVIEW, EarlyView.
Background The interaction between TIGIT and CD155 compromises immune cell efficacy in tumor targeting, potentially driving hepatocellular carcinoma (HCC) progression through diverse molecular pathways. What Was Done This study investigates the interplay between CD155 and TIGIT in regulating CD8+ T cell function and elucidates its implications in HCC ...
Wenting Li   +10 more
wiley   +1 more source

Multifunctional tumor vaccines carrying thalidomide regulate T cell exhaustion and ferroptosis for immunotherapy strategies

open access: yesVIEW, EarlyView.
MTV can greatly achieved antigen presenting cell (APCs), and THA will be released from the polyplex core and enhanced antigen presenting, thereby prompting APC maturation and antigen presenting. The membrane antigens on MTV are degraded into small peptides by proteasomes and presented by MHC complexes.
Anmin Huang   +9 more
wiley   +1 more source

<i>Trichinella spiralis</i>-derived extracellular vesicles induce regulatory T cells and reduce airway allergy in mice. [PDF]

open access: yesFront Immunol
Glamočlija S   +9 more
europepmc   +1 more source

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