Results 351 to 360 of about 199,492 (387)

Cullin-3 and Regulatory Biomolecules Profiling in Vitiligo: Integrated Docking, Clinical, and In Silico Insights. [PDF]

Biomolecules
Abdellatif HAA, Azab M, El-Sayed EH, Halim RMMM, Milebary AJ, Alenizi DA, Fawzy MS, Abd El-Fadeal NM.   +7 more
europepmc   +1 more source

IL‐1R2 Expression in Tfr Cells Controls Allergic Anaphylaxis by Regulating IgG Versus IgE Responses

Allergy, EarlyView.
Paul Engeroff, Aude Belbezier, Romain Vaineau, Gwladys Fourcade, Hugo D. Lujan, Bertrand Bellier, Stephanie Graff‐Dubois, David Klatzmann   +7 more
wiley   +1 more source

Faecalibacterium in the Gut Microbiota Predicts Tolerance Acquisition in Pediatric Hen's Egg Allergy

Allergy, EarlyView.
Shohei Akagawa, Shoji Tsuji, Yoko Nakai, Chika Urakami, Mitsuru Yamagishi, Yuko Akagawa, Kazunari Kaneko   +6 more
wiley   +1 more source

FoxP3 partners up [PDF]

Nature Immunology, 2017
By switching its partners, FoxP3 segregates into functional and non-functional transcriptional complexes.
David Bending, Masahiro Ono
openaire   +2 more sources

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Polymorphism of the ovine FOXP3 gene (FOXP3)

Veterinary Immunology and Immunopathology, 2011
FOXP3 is a transcription factor predominantly expressed in CD4(+) CD25(+) thymocytes and CD4(+) CD25(+) peripheral T cells. It has been reported that variation in the FOXP3 gene (FOXP3) could cause impaired immune regulation. Using PCR-SSCP, variation in exon 4, exon 9-10 and exon 13-14 of ovine FOXP3, covering three functional domains (a proline rich ...
Jon G.H. Hickford, Huitong Zhou, Guo Yang   +2 more
openaire   +3 more sources

Functional Analysis of FOXP3

Annals of the New York Academy of Sciences, 2008
Tolerance to self antigens is established in two ways: first in the thymus through the deletion of thymocytes expressing self‐reactive T cell receptors; and second, in the periphery through multiple mechanisms involving deletion, anergy, and suppression.
Steven F. Ziegler, Jane H. Buckner
openaire   +2 more sources

Role of Activin A in the Induction of Foxp3+ and Foxp3− CD4+ Regulatory T Cells

Critical Reviews™ in Immunology, 2011
Regulatory T cells (Tregs) play a crucial role in the maintenance of immune homeostasis. The two best studied types of CD4(+) regulatory T cells are the Foxp3(+) Tregs and the T regulatory type 1 (Tr1) cells. CD4(+) regulatory T cells play a protective role in autoimmune disease. On the other hand, they also may have pathogenic properties in infectious
Christoph Schramm, Samuel Huber
openaire   +3 more sources

FOXP3+ regulatory T cells: control of FOXP3 expression by pharmacological agents

Trends in Pharmacological Sciences, 2011
Naturally arising CD4(+)CD25(+) regulatory T cells (Tregs), which specifically express the forkhead family transcription factor FOXP3, are essential for the maintenance of immunological self-tolerance and immune homeostasis. Tregs can suppress the activation, proliferation and effector function of other lymphocytes in physiological and pathological ...
Naganari Ohkura, Naganari Ohkura, Masahide Hamaguchi, Masahide Hamaguchi, Shimon Sakaguchi, Shimon Sakaguchi   +5 more
openaire   +3 more sources

FOXP3 and its partners: structural and biochemical insights into the regulation of FOXP3 activity

Immunologic Research, 2008
Forkhead box protein P3 (FOXP3) contributes to a unique transcriptional signature and serves as a functional marker of CD4(+)CD25(+) natural regulatory T cells. Dysfunction of FOXP3 in human is associated with fatal autoimmune disease known as immunodysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) or X-linked autoimmunity ...
Bin Li, Mark I. Greene, Xiaomin Song, Zhaocai Zhou   +3 more
openaire   +3 more sources