Results 91 to 100 of about 210,852 (219)
Cybernetics and Information Technologies, 2020 In recent years, due to its non-volatile memory, non-locality, and weak singularity features, fractional calculations have begun to take place frequently in artificial neural network implementations and learning algorithms. Therefore, there is a need for
Taşkıran Zehra Gülru Çam +1 more
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Experimental Characterization of Ionic Polymer Metal Composite as a Novel Fractional Order Element
Advances in Mathematical Physics, 2013 Ionic polymer metal composites (IPMCs) are electroactive materials made of ionic polymer thin membranes with platinum metallization on their surfaces. They are interesting materials due to not only their electromechanical applications as transducers but ...
Riccardo Caponetto +3 more
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Multifunctional Electronically Reconfigurable and Tunable Fractional-Order Filter
Elektronika ir Elektrotechnika, 2019 In this paper the authors present a multifunctional reconfigurable fractional-order filter performing a low-pass, high-pass, band-pass and band-reject transfer function.
Jan Dvorak +4 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
MathematicsThis paper presents a new method for the simultaneous estimation of system states and unknown inputs in fractional-order Takagi–Sugeno (FO-TS) systems with unmeasurable premise variables (UPVs), by introducing a fractional-order proportional-integral ...
Abdelghani Djeddi +3 more
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A wellbore creep model based on the fractional viscoelastic constitutive equation
Petroleum Exploration and Development, 2017 To simulate the evolution of wellbore creep accurately, predict and prevent severe accidents such as borehole wall sloughing, casing collapse and sticking of the drill, based on previous studies, the springpot element was introduced into the classical ...
Yu PENG, Jinzhou ZHAO, Yongming LI
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Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source