Results 91 to 100 of about 10,729,116 (245)

A Creep Model of Asphalt Mixture Based on Variable Order Fractional Derivative

open access: yesApplied Sciences, 2020
In order to quantitatively describe the time-varying mechanical properties of asphalt mixture during creep process, a nonlinear viscoelastoplastic creep model was proposed, by using variable-order fractional calculus.
Wenbo Luo   +4 more
doaj   +1 more source

The Fractional Ornstein-Uhlenbeck Process: Term Structure Theory and Application [PDF]

open access: yes
The paper revisits dynamic term structure models (DTSMs) and proposes a new way in dealing with the limitation of the classical affine models. In particular, this paper expands the flexibility of the DTSMs by applying a fractional Brownian motion as the ...
Frederiksen, Per H., Høg, Espen P.
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Multifunctional Electronically Reconfigurable and Tunable Fractional-Order Filter

open access: yesElektronika ir Elektrotechnika, 2019
In this paper the authors present a multifunctional reconfigurable fractional-order filter performing a low-pass, high-pass, band-pass and band-reject transfer function.
Jan Dvorak   +4 more
doaj   +1 more source

The Fractional OU Process: Term Structure Theory and Application [PDF]

open access: yes
The paper revisits dynamic term structure models (DTSMs) and proposes a new way in dealing with the limitation of the classical affine models. In particular, this paper expands the flexibility of the DTSMs by applying a fractional Brownian motion as the ...
Esben Hoeg, Per Frederiksen
core  

Exploring vibrational resonance in biophysical systems with fractional-order damping [PDF]

open access: yes
Vibrational Resonance (VR), which is characterised by the enhancement of the maximum response of a weakly driven system’s output signal induced by a high-frequency (HF) periodic signal, was numerically examined in a bi-harmonically driven dimensionless ...
Oyero, B. A.   +5 more
core   +1 more source

A finite element method for time fractional partial differential equations [PDF]

open access: yes, 2011
This is the authors' PDF version of an article published in Fractional calculus and applied analysis© 2011. The original publication is available at www.springerlink.comThis article considers the finite element method for time fractional differential ...
Yan, Yubin   +5 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Finite Element Solutions for the Space Fractional Diffusion Equation with a Nonlinear Source Term

open access: yesAbstract and Applied Analysis, 2012
We consider finite element Galerkin solutions for the space fractional diffusion equation with a nonlinear source term. Existence, stability, and order of convergence of approximate solutions for the backward Euler fully discrete scheme have been ...
Y. J. Choi, S. K. Chung
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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