Results 31 to 40 of about 710 (236)

Modeling and Analysis of Caputo–Fabrizio Definition-Based Fractional-Order Boost Converter with Inductive Loads

Fractal and Fractional
This paper proposes a modeling and analysis method for a Caputo–Fabrizio (C-F) definition-based fractional-order Boost converter with fractional-order inductive loads.
Donghui Yu, Xiaozhong Liao, Yong Wang
doaj   +1 more source

Two Predictive Current Controls for Fractional Boost Converters

四川大学学报. 自然科学版, 2021
Based on the theory of fractional calculus and the fact that actual capacitance and actual inductance are fractional in nature. Firstly，based on the establishment of a fractionalorder mathematical model of the Boost converter, a fractionalorder ...
WANG Yun-Jian, HUO Xing-Xing, ZHANG Wei
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Basic elements of brain-like computing: From memristor to fracmemristor

四川大学学报. 自然科学版, 2020
In this paper, fractional-order memristor (fracmemristor), a novel basic element of brain-like computing, is discussed.The concept of memristor is extended from the conventional integer order to the fractional order, i.e. the fracmemristor. Fracmemristor
PU Yi-Fei, YU Bo, YUAN Xiao
doaj  

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Fractional-Order LCL Filters: Principle, Frequency Characteristics, and Their Analysis

Fractal and Fractional
The fractional-order LCL filter, composed of two fractional-order inductors and one fractional-order capacitor, is a novel fractional-order π-type circuit introduced in recent years.
Junhua Xu, Ermeng Zeng, Xiaocong Li, Guopeng He, Weixun Liu, Xuanren Meng   +5 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Measurement Units and Physical Dimensions of Fractance-Part II: Fractional-Order Measurement Units and Physical Dimensions of Fractance and Rules for Fractors in Series and Parallel

IEEE Access, 2016
Here and in the companion paper (Part I), a novel conceptual framework on the measurement units and physical dimensions of fractance and rules for fractors in series and parallel is mainly discussed.
Yi-Fei Pu
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source