Results 51 to 60 of about 173,678,394 (266)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

MOESM2 of Oscillation-specific nodal alterations in early to middle stages Parkinson’s disease

, 2019
Additional file 2. The effect of oscillatory frequencies on fractional amplitude of low-frequency fluctuation (fALFF) in patients with Parkinson’s disease and normal controls (p  10)
Chunlei Liu (57542), Jiali Pu (445199), Baorong Zhang (445204), Qiaoling Zeng (5205488), Jiaqiu Wang (839013), Xiaojun Guan (26241), Quanquan Gu (299323), Hongjiang Wei (383745), Peiyu Huang (408465), Yuyao Zhang (594655), Min-Ming Zhang (5724395), Xiaojun Xu (153741), Cheng Zhou (307152), Min Xuan (299322), Tao Guo (126667)   +14 more
core   +1 more source

Reduced Brain Activity in the Right Putamen as an Early Predictor for Treatment Response in Drug-Naive, First-Episode Schizophrenia

Frontiers in Psychiatry, 2019
Antipsychotic medications can have a significant effect on brain function after only several days of treatment. It is unclear whether such an acute effect can serve as an early predictor for treatment response in schizophrenia.
Renrong Wu, Renrong Wu, Yangpan Ou, Yangpan Ou, Feng Liu, Jindong Chen, Jindong Chen, Huabing Li, Jingping Zhao, Jingping Zhao, Wenbin Guo, Wenbin Guo, Xiaoduo Fan   +12 more
doaj   +1 more source

The effects of Alzheimer's disease related striatal pathologic changes on the fractional amplitude of low-frequency fluctuations

Computer Methods in Biomechanics and Biomedical Engineering, 2020
This paper aims to correlate Alzheimer's disease (AD) related striatal pathologic changes with the fractional amplitude of low-frequency fluctuations (fALLF) in the blood oxygenation level-dependent (BOLD) signal in the resting state functional Magnetic Resonance Imaging (rs-fMRI).
openaire   +4 more sources

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Stable electro-optic frequency comb generation using an ultrahigh finesse etalon filtered optoelectronic oscillator

, 2018
In this work we investigate the overall stability of tunable, broadband electro-optic frequency combs created in an optoelectronic oscillator filtered with an ultra-high finesse Fabry-Perot etalon.
Peter J. Delfyett, Michael E. Plascak, Delfyett, Peter J., Ricardo Bustos Ramirez, Plascak, Michael E., Bustos Ramirez, Ricardo   +5 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Correlation between the amplitude of low-frequency fluctuation (ALFF) of EZ and the abnormal driven effect on it in patients (A) and controls (B).

, 2013
Correlation between the amplitude of low-frequency fluctuation (ALFF) of EZ and the abnormal driven effect on it in patients (A) and controls (B).
Han Zhang (110653), Zhiqiang Zhang (1522858), Gong-Jun Ji (587418), Yu-Feng Zang (134040), Guangming Lu (1396030), Wei Liao (166135), Jue Wang (58890), Dong-Qiang Liu (294614)   +7 more
core   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Low-complexity LSMR equalisation of FrFT-based multicarrier systems in doubly dispersive channels [PDF]

, 2011
The discrete fractional Fourier transform (FrFT) has been suggested to enhance performance over DFT-based multicarrier systems when transmitting over doubly-dispersive channels.
Weiss, Stephan, Stephan Weiss, Soraghan, John, Solyman, Ahmed A. A., Solyman, Ahmed, Soraghan, John J., John J. Soraghan, Ahmed A. A. Solyman   +7 more
core   +1 more source