Results 41 to 50 of about 166,029,081 (260)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A solution to a fractional order semilinear equation using variational method

open access: yesMathematics in Applied Sciences and Engineering, 2020
We will discuss how we obtain a solution to a semilinear pseudo-differential equation involving fractional power of laplacian by using a method analogous to the direct method of calculus of variations.
Ramesh Karki, Young Hwan You
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Necessary optimality conditions for fractional action-like problems with intrinsic and observer times [PDF]

open access: yes, 2008
We prove higher-order Euler-Lagrange and DuBois-Reymond stationary conditions to fractional action-like variational problems.
Frederico, G.S.F., Torres, D.F.M.
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Fractional Calculus of Variations in Terms of a Generalized Fractional Integral with Applications to Physics

open access: yesAbstract and Applied Analysis, 2012
We study fractional variational problems in terms of a generalized fractional integral with Lagrangians depending on classical derivatives, generalized fractional integrals and derivatives.
Tatiana Odzijewicz   +2 more
doaj   +1 more source

Fractional-Order Extremum Seeking Method for Maximum Torque per Ampere Control of Permanent Magnet Synchronous Motor

open access: yesFractal and Fractional, 2023
Maximum torque per ampere (MTPA) control of internal permanent magnet synchronous motors (IPMSM) has become integral to high-efficiency motor drives. To minimize the influence of the traditional model-based analytical solution method on the MTPA control ...
Haiying Song   +4 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Ergodicity of hypoeliptic SDEs driven by fractional Brownian motion [PDF]

open access: yes, 2009
We demonstrate that stochastic differential equations (SDEs) driven by fractional Brownian motion with Hurst parameter H > 1/2 have similar ergodic properties as SDEs driven by standard Brownian motion.
Hairer, Martin, Pillai, Natesh S.
core  

Applications of the Fractional Calculus: On a Discretization of Fractional Diffusion Equation in One Dimension

open access: yes, 2010
The paper discusses the problem of classical and fractional diffusion models. It is known that the classical model fails in heterogeneous structures with locations where particles move at a large speed over a long distance.
Tomas Kisela
core   +1 more source

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