Results 71 to 80 of about 166,029,081 (260)

Dynamic Analysis of a Fractional-Order Economic Model: Chaos and Control

Fractal and Fractional
Fractional calculus in discrete-time is a recent field that has drawn much interest for dealing with multidisciplinary systems. A result of this tremendous potential, researchers have been using constant and variable-order fractional discrete calculus in
Ali Aloui, Louiza Diabi, Omar Kahouli, Adel Ouannas, Lilia El Amraoui, Mohamed Ayari   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Fractional-Order Deterministic Learning for Fast and Robust Detection of Sub-Synchronous Oscillations in Wind Power Systems

Mathematics
This work explores the issue of identifying sub-synchronous oscillations (SSOs). Regular detection techniques face issues with response timings to variations in viewpoint and adaptability to variations in conditions of the system but our proposed method ...
Omar Kahouli, Lilia El Amraoui, Mohamed Ayari, Omar Naifar   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Calculus of variations: A differential form approach

We study integrals of the form integral(Omega) f(d omega(1), ..., d omega(m)), where m >= 1 is a given integer, 1 R is a continuous function. We introduce the appropriate notions of convexity, namely vectorial ext.
Sil, Swarnendu
core   +1 more source

Fractional robust control with iso-damping property [PDF]

, 2008
This article deals with the problem of the reduction of structural vibrations with isodamping property. The proposed methodology is based on: - a contour defined in the Nichols plane and significant of the damping ratio of the closed-loop response - a ...
Janat, Yaman, Oustaloup, Alain, Pommier-Budinger, Valérie, A. Oustaloup, V. Pommier-Budinger, D. Nelson-Gruel, Lanusse, Patrick, Nelson-Gruel, Dominique, Y. Janat, P. Lanusse   +9 more
core   +1 more source

Weighted fractional Euler–Maclaurin inequalities for convex and bounded variation functions via Riemann–Liouville integrals

Journal of Inequalities and Applications
This paper develops weighted Euler–Maclaurin-type inequalities using Riemann–Liouville fractional integrals for classes of differentiable convex functions and functions of bounded variation.
Areej A. Almoneef, Abd-Allah Hyder, Fatih Hezenci, Hüseyin Budak   +3 more
doaj   +1 more source

Legendre–Clebsch Condition for Functional Involving Fractional Derivatives with a General Analytic Kernel

Fractal and Fractional
Fractional calculus of variations for a broad class of fractional operators with a general analytic kernel function is considered. Using techniques from variational analysis, we derive first- and second-order necessary optimality conditions, namely the ...
Faïçal Ndaïrou
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source