Results 71 to 80 of about 1,884 (305)

Ergodicity of hypoeliptic SDEs driven by fractional Brownian motion [PDF]

open access: yes, 2009
We demonstrate that stochastic differential equations (SDEs) driven by fractional Brownian motion with Hurst parameter H > 1/2 have similar ergodic properties as SDEs driven by standard Brownian motion.
Hairer, Martin, Pillai, Natesh S.
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A necessary optimality condition for extended weighted generalized fractional optimal control problems

open access: yesResults in Control and Optimization
Using the recent weighted generalized fractional order operators of Hattaf, a general fractional optimal control problem without constraints on the values of the control functions is formulated and a corresponding (weak) version of Pontryagin’s maximum ...
Houssine Zine   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Extended fractional calculus of variations, complexified geodesics and Wong’s fractional equations on complex plane and on Lie algebroids

open access: yes, 2016
In this work, we communicate the topic of complex Lie algebroids based on the extended fractional calculus of variations in the complex plane. The complexified Euler-Lagrange geodesics and Wong’s fractional equations are derived.
El-Nabulsi, Ahmad Rami
core   +2 more sources

A solution to a fractional order semilinear equation using variational method

open access: yesMathematics in Applied Sciences and Engineering, 2020
We will discuss how we obtain a solution to a semilinear pseudo-differential equation involving fractional power of laplacian by using a method analogous to the direct method of calculus of variations.
Ramesh Karki, Young Hwan You
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Fractional-Order Extremum Seeking Method for Maximum Torque per Ampere Control of Permanent Magnet Synchronous Motor

open access: yesFractal and Fractional, 2023
Maximum torque per ampere (MTPA) control of internal permanent magnet synchronous motors (IPMSM) has become integral to high-efficiency motor drives. To minimize the influence of the traditional model-based analytical solution method on the MTPA control ...
Haiying Song   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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