Results 51 to 60 of about 2,135,059 (291)
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Update on CO2 Laser Ablation of Polyoxymethylene [PDF]
, 2010 Polyoxymethylene (POM) propellants have been studied since the 1970's, and perhaps represent the most promising match of a propellant to the CO2 laser for laser propulsion studies.
Sinko, John Elihu +5 more
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FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Periocular syringomas – Successful treatment with fractional CO2 laser [PDF]
, 2017 <p>Syringoma is a benign tumor of eccrine origin which arises from eccrine ducts. Syringomas are most commonly found on the eyelids in middle-aged women. Traditional treatments include surgical excision, curettage, peelings, dermabrasion and laser.
Alberto Goldman, Uwe Wollina
core +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Hand Rejuvenation by Ablative Fraction CO2 Laser
Journal of Skin and Stem Cell, 2014 Background: Ablative fractional CO2 laser (AFCL) has been reported to be safe and effective to use for preventing hand photoaging in a recent pilot study. Objectives: This study aimed to evaluate the efficacy of AFCL in improvement of hand photoaging in 25 patients. Patients and Methods: A prospective, before- after, single blind study was conducted in
Elham Behrangi +5 more
openaire +1 more source
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
FEBS Open Bio, EarlyView.Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
, 2020 original article A SPLIT FACE COMPARATIVE STUDY OF MICRONEEDING WITH PLATELET RICH PLASMA VERSUS FRACTIONAL CO2 LASER WITH PLATELET RICH PLASMA IN MANAGEMENT OF ATROPHIC ACNE SCARSoriginal article A SPLIT FACE COMPARATIVE STUDY OF MICRONEEDING WITH ...
Dr Jigna Barot +3 more
core +1 more source
Advanced Engineering Materials, EarlyView.This study proposes a potential device design for joint cartilage replacement. Silica‐polytetrahydrofuran (SiO2‐PolyTHF) hybrids with customizable mechanical properties were developed to mimic the characteristics of a natural meniscus. These were synthesized through a two‐pot sol–gel hybrid process.
Yu‐Chien Lin +12 more
wiley +1 more source
Evaluation of Fractional CO2 Laser Efficacy in Acne Scar [PDF]
, 2012 INTRODUCTION: Acne scar is formed after severe episodes of acne in teen and earlyadult years. Several treatment options have been used for depressed acne scars suchas punch grafting, punch excision carbon dioxide (CO2) laser etc.
Mohebbi, Azadeh, Saryazdi, Simin
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