Results 111 to 120 of about 187,262 (303)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

A note on fractional derivatives and fractional powers of operators

open access: yesJournal of Mathematical Analysis and Applications, 2009
AbstractDefinitions of fractional derivatives and fractional powers of positive operators are considered. The connection of fractional derivatives with fractional powers of positive operators is presented. The formula for fractional difference derivative is obtained.
openaire   +2 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

New Approach for the Analysis of Damped Vibrations of Fractional Oscillators

open access: yesShock and Vibration, 2009
The dynamic behavior of linear and nonlinear mechanical oscillators with constitutive equations involving fractional derivatives defined as a fractional power of the operator of conventional time-derivative is considered.
Yuriy A. Rossikhin, Marina V. Shitikova
doaj   +1 more source

Time fractional IHCP with Caputo fractional derivatives

open access: yesComputers & Mathematics with Applications, 2008
AbstractThe numerical solution of the time fractional inverse heat conduction problem (TFIHCP) on a finite slab is investigated in the presence of measured (noisy) data when the time fractional derivative is interpreted in the sense of Caputo. A finite difference space marching scheme with adaptive regularization, using mollification techniques, is ...
openaire   +2 more sources

On the definition of fractional derivatives in rheology

open access: yesTheoretical and Applied Mechanics Letters, 2011
AbstractDuring the last two decades fractional calculus has been increasingly applied to physics, especially to rheology. It is well known that there are obivious differences between Riemann-Liouville (R-L) definition and Caputo definition, which are the two most commonly used definitions of fractional derivatives.
Fan Yang, Fan Yang, Ke-Qin Zhu
openaire   +2 more sources

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Numerical simulation of variable-order fractal-fractional delay differential equations with nonsingular derivative

open access: yesEngineering Science and Technology, an International Journal, 2023
This work develops a new Legendre delay operational matrix based on Legendre polynomial features that are integrated with regard to the Legendre fractional derivative operational matrix in order to solve the issues.
Mays Basim   +3 more
doaj  

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