Results 61 to 70 of about 2,240 (300)

On an Inequality of H. G. Hardy

open access: yesJournal of Inequalities and Applications, 2010
We state, prove, and discuss new general inequality for convex and increasing functions. As a special case of that general result, we obtain new fractional inequalities involving fractional integrals and derivatives of Riemann-Liouville type ...
Krulić Kristina   +2 more
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Statistical Distribution Theory and Fractional Calculus

open access: yesStats
This is an overview paper. This paper is an attempt to show that fractional calculus can be reached through statistical distribution theory. This paper brings together results on fractional integrals and fractional derivatives of the first and second ...
A. M. Mathai
doaj   +1 more source

Fractional Calculus of Variations in Terms of a Generalized Fractional Integral with Applications to Physics

open access: yesAbstract and Applied Analysis, 2012
We study fractional variational problems in terms of a generalized fractional integral with Lagrangians depending on classical derivatives, generalized fractional integrals and derivatives.
Tatiana Odzijewicz   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

On fractional derivatives with generalized Mittag-Leffler kernels

open access: yesAdvances in Difference Equations, 2018
Fractional derivatives with three parameter generalized Mittag-Leffler kernels and their properties are studied. The corresponding integral operators are obtained with the help of Laplace transforms.
Thabet Abdeljawad, Dumitru Baleanu
doaj   +1 more source

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