Results 81 to 90 of about 2,240 (300)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
On more general forms of proportional fractional operators
Open Mathematics, 2020 In this article, more general types of fractional proportional integrals and derivatives are proposed. Some properties of these operators are discussed.
Jarad Fahd +2 more
doaj +1 more source
Induction Motor Drive Using Fractional-Order Proportional Integral Derivative (FOPID) Controller Based on Nelder-Mead and Grey Wolf Optimizers. (Dept. E) [PDF]
, 2021 Mohamed El-Sayed M. Essa +2 more
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Fractal and Fractional, 2017 This paper proposes the definition of fractional definite integral and analyses the corresponding fundamental theorem of fractional calculus. In this context, we studied the relevant properties of the fractional derivatives that lead to such a definition.
Manuel Ortigueira, José Machado
doaj +1 more source
Some Applications of Fractional Integral Operators and Ruscheweyh Derivatives
Journal of Mathematical Analysis and Applications, 1996 Recently, \textit{S. Owa}, \textit{M. Saigo} and the third author [J. Math. Anal. Appl. 140, 419-426 (1989; Zbl 0668.30013)] introduced and studied a certain generalized fractional integral operator \(J^{\alpha, \beta, \eta}_{0, z}\) involving the Gaussian hypergeometric function.
Kim, Yong Chan +2 more
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Some Fractional q-Integrals and q-Derivatives [PDF]
Proceedings of the Edinburgh Mathematical Society, 1966 A q-analogue of the integral ∣f(t)dt is defined by means ofwhich is an inverse of the q–derivativeThe present author (2) has recently obtained a q–nalogue of a formula of Cauchy, namely,where, for real or complex α and N a positive integer,
openaire +1 more source