Results 81 to 90 of about 1,811 (235)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Riesz potential and Riemann-Liouville fractional integrals and derivatives of Jacobi polynomials [PDF]

open access: yes, 1997
A generalized fractional Riesz potential of Jacobi polynomials is evaluated. From this formula, Riemann-Lioville fractional integrals and derivatives of weighted Jacobi polynomials are obtained as particular ...
Podlubny, I.
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

On fractional derivatives with generalized Mittag-Leffler kernels

open access: yesAdvances in Difference Equations, 2018
Fractional derivatives with three parameter generalized Mittag-Leffler kernels and their properties are studied. The corresponding integral operators are obtained with the help of Laplace transforms.
Thabet Abdeljawad, Dumitru Baleanu
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Existence of Positive Solutions for a System of Singular Fractional Boundary Value Problems with p-Laplacian Operators

open access: yesMathematics, 2020
We investigate the existence and multiplicity of positive solutions for a system of Riemann–Liouville fractional differential equations with singular nonnegative nonlinearities and p-Laplacian operators, subject to nonlocal boundary conditions which ...
Ahmed Alsaedi, Rodica Luca, Bashir Ahmad
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

High-accuracy numerical integration methods for fractional order derivatives and integrals computations [PDF]

open access: yes, 2014
In this paper the authors present highly accurate and remarkably efficient computational methods for fractional order derivatives and integrals applying Riemann-Liouville and Caputo formulae: the Gauss-Jacobi Quadrature with adopted weight function, the ...
Ostalczyk, Piotr   +3 more
core   +3 more sources

Generalized Fractional ρ,k,φ-Proportional Hilfer Derivatives and Some Properties

open access: yesJournal of Mathematics
Building on previous work in fractional calculus, this paper introduces new definitions for the ρ,k,φ-proportional integral and ρ,k,φ-proportional H fractional derivative.
Haihua Wang
doaj   +1 more source

An Expansion Formula with Higher-Order Derivatives for Fractional Operators of Variable Order

open access: yesThe Scientific World Journal, 2013
We obtain approximation formulas for fractional integrals and derivatives of Riemann-Liouville and Marchaud types with a variable fractional order. The approximations involve integer-order derivatives only. An estimation for the error is given.
Ricardo Almeida, Delfim F. M. Torres
doaj   +1 more source

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