Results 71 to 80 of about 2,240 (300)
Properties of a subclass of analytic functions defined by Riemann-Liouville fractional integral applied to convolution product of multiplier transformation and Ruscheweyh derivative [PDF]
, 2023 Alina Alb Lupaş, Mugur Acu
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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Generalized Fractional ρ,k,φ-Proportional Hilfer Derivatives and Some Properties
Journal of MathematicsBuilding on previous work in fractional calculus, this paper introduces new definitions for the ρ,k,φ-proportional integral and ρ,k,φ-proportional H fractional derivative.
Haihua Wang
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Mathematics, 2020 We investigate the existence and multiplicity of positive solutions for a system of Riemann–Liouville fractional differential equations with singular nonnegative nonlinearities and p-Laplacian operators, subject to nonlocal boundary conditions which ...
Ahmed Alsaedi, Rodica Luca, Bashir Ahmad
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
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An Expansion Formula with Higher-Order Derivatives for Fractional Operators of Variable Order
The Scientific World Journal, 2013 We obtain approximation formulas for fractional integrals and derivatives of Riemann-Liouville and Marchaud types with a variable fractional order. The approximations involve integer-order derivatives only. An estimation for the error is given.
Ricardo Almeida, Delfim F. M. Torres
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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Type of Leibniz Rule on Riemann-Liouville Variable-Order Fractional\n Integral and Derivative Operator [PDF]
, 2021 Dagnachew Jenber, Mollalign Haile
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