Results 71 to 80 of about 1,811 (235)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
On an Inequality of H. G. Hardy
Journal of Inequalities and Applications, 2010 We state, prove, and discuss new general inequality for convex and increasing functions. As a special case of that general result, we obtain new fractional inequalities involving fractional integrals and derivatives of Riemann-Liouville type ...
Krulić Kristina +2 more
doaj
Spectral approximations to the fractional integral and derivative [PDF]
Fractional Calculus and Applied Analysis, 2012 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Li, Changpin, Zeng, Fanhai, Liu, Fawang
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Statistical Distribution Theory and Fractional Calculus
StatsThis is an overview paper. This paper is an attempt to show that fractional calculus can be reached through statistical distribution theory. This paper brings together results on fractional integrals and fractional derivatives of the first and second ...
A. M. Mathai
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Fractal and Fractional, 2022 In this paper, we study the existence of positive solutions for a system of fractional differential equations with ρ-Laplacian operators, Riemann–Liouville derivatives of diverse orders and general nonlinearities which depend on several fractional ...
Alexandru Tudorache, Rodica Luca
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Abstract and Applied Analysis, 2012 We study fractional variational problems in terms of a generalized fractional integral with Lagrangians depending on classical derivatives, generalized fractional integrals and derivatives.
Tatiana Odzijewicz +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Model-Driven Applications of Fractional Derivatives and Integrals
CoRR, 2014 Fractional order derivatives and integrals (differintegrals) are viewed from a frequency-domain perspective using the formalism of Riesz, providing a computational tool as well as a way to interpret the operations in the frequency domain. Differintegrals provide a logical extension of current techniques, generalizing the notion of integral and ...
William A. Sethares, Selçuk S. Bayin
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