Results 91 to 100 of about 2,428 (290)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Further properties of Osler's generalized fractional integrals and derivatives with respect to another function [PDF]
, 2019 In this paper we discuss fractional integrals and fractional derivatives of a function with respect to another function. We present some fundamental properties for both types of fractional operators, such as Taylor’s theorem, Leibniz and semigroup ...
Almeida, Ricardo
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
On more general forms of proportional fractional operators
Open Mathematics, 2020 In this article, more general types of fractional proportional integrals and derivatives are proposed. Some properties of these operators are discussed.
Jarad Fahd +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Fractal and Fractional, 2017 This paper proposes the definition of fractional definite integral and analyses the corresponding fundamental theorem of fractional calculus. In this context, we studied the relevant properties of the fractional derivatives that lead to such a definition.
Manuel Ortigueira, José Machado
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Integrated technology fractional order proportional-integral-derivative design
Journal of Vibration and Control, 2013 In this paper an integrated circuit (IC) design of the fractional order proportional-integral-derivative (PID) controller is proposed. The development of the IC device is realized in Cadence environment, using the switched capacitors (SC) technology in order to reduce the area on the silicon wafer and to improve the electrical controllability. In order
CAPONETTO, Riccardo +3 more
openaire +2 more sources
, 2008 We prove higher-order Euler-Lagrange and DuBois-Reymond stationary conditions to fractional action-like variational problems.
Frederico, G.S.F., Torres, D.F.M.
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