Results 101 to 110 of about 2,428 (290)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Fractional Representation Formulae Under Initial Conditions and Fractional Ostrowski Type Inequalities

Demonstratio Mathematica, 2015
Here we present very general fractional representation formulae for a function in terms of the fractional Riemann-Liouville integrals of different orders of the function and its ordinary derivatives under initial conditions.
Anastassiou George A.
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

The Stability of Non-standard Finite Difference Scheme for Solution of Partial Differential Equations of Fractional Order

پژوهش‌های ریاضی, 2015
Fractional derivatives and integrals are new concepts of derivatives and integrals of arbitrary order. Partial differential equations whose derivatives can be of fractional order are called fractional partial differential equations (FPDEs).
M. Arab Ameri, E Mir Mehrabi
doaj  

ДРОБНОЕ ИСЧИСЛЕНИЕ И АППРОКСИМАЦИОННЫЕ МЕТОДЫ В МОДЕЛИРОВАНИИ ДИНАМИЧЕСКИХ СИСТЕМ [PDF]

, 2008
Книга посвящена аппроксимационно-операционным методам моделирования динамических систем дробного и смешанного порядков. Рассмотрены методы аппроксимации сигналов обобщенными полиномами с различными системами базисных функций, построение на основе этих ...
Симак, Лилия Алексеевна, Васильев, Всеволод Викторович   +1 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Riesz potential and Riemann-Liouville fractional integrals and derivatives of Jacobi polynomials

, 1997
A generalized fractional Riesz potential of Jacobi polynomials is evaluated. From this formula, Riemann-Lioville fractional integrals and derivatives of weighted Jacobi polynomials are obtained as particular ...
Podlubny, I.
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Some Fractional Integral and Derivative Formulas Revisited

Mathematics
In the most common literature about fractional calculus, we find that Dtαaft=It−αaft is assumed implicitly in the tables of fractional integrals and derivatives. However, this is not straightforward from the definitions of Itαaft and Dtαaft. In this sense, we prove that Dt0ft=It−α0ft is true for ft=tν−1logt, and ft=eλt, despite the fact that these ...
Juan Luis González-Santander, Francesco Mainardi   +1 more
openaire   +4 more sources

Novel Ostrowski–Type Inequalities for Generalized Fractional Integrals and Diverse Function Classes [PDF]

In this work, novel Ostrowski-type inequalities for dissimilar function classes and generalized fractional integrals (FITs) are presented. We provide a useful identity for differentiable functions under FITs, which results in special expressions for ...
Hüseyin Budak, Hyder, Abd-Allah, Barakat, Mohamed A., Almoneef, Areej A., Budak, Huseyin, Mohamed A. Barakat, Areej A. Almoneef, Abd-Allah Hyder   +7 more
core   +1 more source