Results 51 to 60 of about 281,920 (272)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Finite difference scheme for multi-term variable-order fractional diffusion equation

Advances in Difference Equations, 2018
In this paper, we consider a multi-term variable-order fractional diffusion equation on a finite domain, which involves the Caputo variable-order time fractional derivative of order α(x,t)∈(0,1) $\alpha(x,t) \in(0,1) $ and the Riesz variable-order space ...
Tao Xu, Shujuan Lü, Wenping Chen, Hu Chen   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Analysis of the difference scheme of wave equation equivalent with fractional differentiation operator

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2014
Analysis of the difference scheme of boundary-value problem for the wave equation analogue is made. Explicit and implicit difference schemes for numerical solution of the first boundary-value problem for the wave equation analogue with Caputo fractional ...
Vetlugin D Beybalaev, Amuchi Z Yakubov
doaj   +1 more source

Basics of Qualitative Theory of Linear Fractional Difference Equations [PDF]

, 2012
Tato doktorská práce se zabývá zlomkovým kalkulem na diskrétních množinách, přesněji v rámci takzvaného (q,h)-kalkulu a jeho speciálního případu h-kalkulu.
Kisela, Tomáš
core  

Efficient numerical solution of the time fractional diffusion equation by mapping from its Brownian counterpart

, 2015
The solution of a Caputo time fractional diffusion equation of order ...
Philippa, Bronson, Read, Wayne, Stokes, Peter W., White, Ronald D.   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Time-fractional diffusion of distributed order

, 2007
The partial differential equation of Gaussian diffusion is generalized by using the time-fractional derivative of distributed order between 0 and 1, in both the Riemann-Liouville (R-L) and the Caputo (C) sense.
Gorenflo, Rudolf, Mainardi, Francesco, Mura, Antonio, Pagnini, Gianni   +3 more
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Oscillation results for certain fractional difference equations

Journal of Hebei University of Science and Technology, 2017
Fractional calculus is a theory that studies the properties and application of arbitrary order differentiation and integration. It can describe the physical properties of some systems more accurately, and better adapt to changes in the system, playing an
Zhiyun WANG, Shujuan LIU, Qiaoluan LI
doaj   +1 more source