Results 71 to 80 of about 39,837 (259)

State Estimation of Continuous-Time Linear Fractional-Order Systems Disturbed by Correlated Colored Noises via Tustin Generating Function

open access: yesIEEE Access, 2020
This paper proposes Kalman filters to investigate the state estimation of continuous-time linear fractional-order systems disturbed by correlated colored noises. A difference equation is obtained by discretizing the fractional-order differential equation
Xiaomin Huang   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Explicit Finite Difference Approximation for the TwoDimensional Fractional Dispersion Equation

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2016
  In this paper, we introduce and discuss an algorithm for the numerical solution of two- dimensional fractional dispersion equation.  The algorithm for the numerical solution of this equation is based on explicit finite difference approximation ...
I. I. Gorial
doaj  

Impulsive nabla fractional difference equations

open access: yesFractional Differential Calculus, 2022
Summary: This article deals with the study of impulsive nabla fractional difference equations. First, we present afirst-order initial value problem (IVP) on impulsive nabla difference equations and write its equivalent sum equation. To illustrate the proposed procedure, we provide an example.
openaire   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Equivalent descriptions of a discrete-time fractional-order linear system and its stability domains

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2012
Two description forms of a linear fractional-order discrete system are considered. The first one is by a fractional-order difference equation, whereas the second by a fractional-order state-space equation.
Ostalczyk Piotr
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Solution of the Fractional Black-Scholes Option Pricing Model by Finite Difference Method

open access: yesAbstract and Applied Analysis, 2013
This work deals with the put option pricing problems based on the time-fractional Black-Scholes equation, where the fractional derivative is a so-called modified Riemann-Liouville fractional derivative.
Lina Song, Weiguo Wang
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

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