Results 121 to 130 of about 191,994 (333)

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

On the existence and stability of fuzzy CF variable fractional differential equation for COVID-19 epidemic. [PDF]

Eng Comput, 2022
Verma P, Kumar M.
europepmc   +1 more source

Structural and functional analysis of Bacillus sarcosine oxidase and its activity toward cyclic imino acids

FEBS Open Bio, EarlyView.
Sarcosine oxidase from Bacillus sp. (SoxB) recognizes l‐proline (l‐Pro), d‐proline (d‐Pro), and l‐thioproline (l‐Tpr) as minor substrates. In this study, we measured their absorption spectra, determined the crystal structures of their enzyme complexes, and performed site‐directed mutagenesis of key residues.
Yuqi Zhang, Yoshitaka Nakajima, Masae Kurobe, Tsutomu Nakamura, Tomoki Himiyama, Yoshiaki Nishiya   +5 more
wiley   +1 more source

Fractional Brownian motions ruled by nonlinear equations

, 2018
In this note we consider generalized diffusion equations in which the diffusivity coefficient is not necessarily constant in time, but instead it solves a nonlinear fractional differential equation involving fractional Riemann-Liouville time-derivative ...
Garra, Roberto, Issoglio, Elena, Taverna, Giorgio S.   +2 more
core  

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Symmetry Analysis and Wave Solutions of Time Fractional Kupershmidt Equation

Journal of Applied Mathematics
This study employs the Lie symmetry technique to explore the symmetry features of the time fractional Kupershmidt equation. Specifically, we use the Lie symmetry technique to derive the symmetry generators for this equation, which incorporates a ...
Shalu Saini, Rajeev Kumar, Kamal Kumar
doaj   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Multivariate Padé Approximation for Solving Nonlinear Partial Differential Equations of Fractional Order

Abstract and Applied Analysis, 2013
Two tecHniques were implemented, the Adomian decomposition method (ADM) and multivariate Padé approximation (MPA), for solving nonlinear partial differential equations of fractional order. The fractional derivatives are described in Caputo sense.
Veyis Turut, Nuran Güzel
doaj   +1 more source

Global Stability of a Fractional Partial Differential Equation [PDF]

, 2000
Hana Petzeltová, Jan Prüß
openalex   +1 more source

Fractional Differential Equations

, 2017
Fractional calculus, the branch of mathematics dealing with derivatives and integrals of non-integer order, began as a mere mathematical curiosity during the time of Leibniz but through the years has developed into a very dynamic field of research. Famous mathematicians such as Riemann, Liouville, Grunwald, Euler, Lagrange, Caputo and others laid the ...
openaire   +1 more source