Results 91 to 100 of about 184,534 (322)
Advances in Difference Equations, 2018 In this paper, we investigate oscillatory and asymptotic properties for a class of fractional order dynamic equations on time scales, where the fractional derivative is defined in the sense of the conformable fractional derivative.
Qinghua Feng, Fanwei Meng
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Impulsive Hilfer fractional differential equations
Advances in Difference Equations, 2018 Existence and controllability results for nonlinear Hilfer fractional differential equations are studied. Sufficient conditions for existence and approximate controllability for Sobolev-type impulsive fractional differential equations are established ...
Hamdy M. Ahmed +3 more
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Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
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Ulam–Hyers Stability and Uniqueness for Nonlinear Sequential Fractional Differential Equations Involving Integral Boundary Conditions [PDF]
, 2021 Areen Al-Khateeb +3 more
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Hybrid fractional differential equation with nonlocal and impulsive conditions
, 2023 Khalid Hilal +2 more
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HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Existence and uniqueness of periodic solutions for some nonlinear fractional pantograph differential equations with $$\psi $$-Caputo derivative [PDF]
, 2021 Soufyane Bouriah +3 more
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Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source