Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Implementation of non-linear mixed effects models defined by fractional differential equations. [PDF]
J Pharmacokinet Pharmacodyn, 2023 Kaikousidis C, Dokoumetzidis A.
europepmc +1 more source
Space-time estimates of linear flow and application to some nonlinear integro-differential equations corresponding to fractional-order time derivative [PDF]
, 2002 Hitoshi Hirata, Changxing Miao
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FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Author Correction: Deterministic-stochastic analysis of fractional differential equations malnutrition model with random perturbations and crossover effects. [PDF]
Sci Rep, 2023 Chu YM +4 more
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The Diverse Neuromuscular Spectrum of VPS13A Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective VPS13A disease (chorea‐acanthocytosis) is a rare neurodegenerative disorder caused by biallelic variants in VPS13A, typically presenting with hyperkinetic movement disorders, while neuromuscular signs are often mild. The aim of the project was to investigate the frequency and severity of neuromuscular impairment in VPS13A disease ...
Anne Buchberger +16 more
wiley +1 more source
A new Bihari inequality and initial value problems of first order fractional differential equations. [PDF]
Fract Calc Appl Anal, 2023 Lan K, Webb JRL.
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Fractional differential equations driven by Lévy noise [PDF]
, 2003 Vo Anh, R. McVinish
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Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
wiley +1 more source
Modelling Radiation Cancer Treatment with a Death-Rate Term in Ordinary and Fractional Differential Equations. [PDF]
Bull Math Biol, 2023 Wilson N +4 more
europepmc +1 more source