Results 71 to 80 of about 184,534 (322)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Mathematical modelling of unsteady fractional Phan Thien Tanner fluid

Alexandria Engineering Journal, 2020
The fractional calculus approach in the constitutive relationship model of viscoelastic fluid is introduced. For the first time, unsteady fractional Phan Thien Tanner fluid is modeled, which results in different space-time nonlinear fractional partial ...
Naeem Faraz, Yasir Khan, Amna Anjum
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Analyzing fuzzy fractional Degasperis–Procesi and Camassa–Holm equations with the Atangana–Baleanu operator

Open Physics
This article presents a new approach for solving the fuzzy fractional Degasperis–Procesi (FFDP) and Camassa–Holm equations using the iterative transform method (ITM). The fractional Degasperis–Procesi (DP) and Camassa–Holm equations are extended from the
Alshehry Azzh Saad, Yasmin Humaira, Shah Manzoor Ali, Shah Rasool   +3 more
doaj   +1 more source

Existence of solutions for integral boundary value problems of mixed fractional differential equations under resonance [PDF]

, 2020
Shiying Song, Yujun Cui
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Approximate Time‐Fractional Differential Equations

Discrete Dynamics in Nature and Society
This study introduces an indirect approach to find the solutions of the fractional Bessel differential equation using fractional Bernoulli functions and Caputo’s fractional derivative. This method transforms the problem into a nonlinear system of algebraic equations. The existence and uniqueness of the solution for the problem are proved.
Saber Tavan, Mohammad Jahangiri Rad, Ali Salimi Shamloo, Yaghoub Mahmoudi   +3 more
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The Rishi Transform method for solving multi-high order fractional differential equations with constant coefficients

AIMS Mathematics
In this paper, we suggest the Rishi transform, which may be used to find the analytic (exact) solution to multi-high-order linear fractional differential equations, where the Riemann-Liouville and Caputo fractional derivatives are used.
Ali Turab, Hozan Hilmi, Juan L.G. Guirao, Shabaz Jalil, Nejmeddine Chorfi, Pshtiwan Othman Mohammed   +5 more
doaj   +1 more source