Results 41 to 50 of about 10,103 (245)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A numerical scheme for fractional order mortgage model of economics
Results in Applied Mathematics, 2023 In this article, the famous mortgage model of economics is investigated by developing a numerical scheme. The considered model is proposed under the Caputo power law derivative of fractional order.
Hafsa Naz +4 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Design of a fractional control using performance contours. Application to an electromechanical system [PDF]
, 2003 The article proposes a frequency-based method to design a controller ensuring dynamic behavior of a closed-loop control: the first overshoot of the step response in the tracking mode or in the regulation mode, the damping ratio and the natural frequency ...
Oustaloup, Alain +2 more
core
, 2010 The multiindex Mittag-Leffler (M-L) function and the multiindex Dzrbashjan-Gelfond-Leontiev (D-G-L) differentiation and integration play a very pivotal role in the theory and applications of generalized fractional calculus. The object of this paper is to
U.K. Saha, L.K. Arora
core +1 more source
On certain fractional calculus operators involving generalized Mittag-Leffler function [PDF]
Sahand Communications in Mathematical Analysis, 2016 The object of this paper is to establish certain generalized fractional integration and differentiation involving generalized Mittag-Leffler function defined by Salim and Faraj [25].
Dinesh Kumar
doaj
Fractal and Fractional, 2022 In this paper, in the class of smooth functions, integration and differentiation operators connected with fractional conformable derivatives are introduced.
Kairat Usmanov +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
پژوهشهای ریاضی, 2022 The fractional calculus deals with the generalization of integration and differentiation of integer order to those ones of any order. The q-fractional differential equation usually describe the physical process imposed on the time scale set Tq.
اعظم فتحی پور, azam fathipour
doaj
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source