Results 101 to 110 of about 19,043 (300)

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Objective Identification of Intermediate Lesions Inducing Myocardial Ischemia Using Sequential Intracoronary Pressure and Flow Measurements

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Although ischemic heart disease has a complex and multilevel origin, the diagnostic approach is mainly focused on focal obstructive disease as assessed by pressure‐derived indexes.
Valérie E. Stegehuis, Gilbert W. M. Wijntjens, Sukhjinder S. Nijjer, Guus A. de Waard, Tim P. van de Hoef, Sayan Sen, Ricardo Petraco, Mauro Echavarría‐Pinto, Martijn Meuwissen, Ibrahim Danad, Paul Knaapen, Javier Escaned, Justin E. Davies, Niels van Royen, Jan J. Piek   +14 more
doaj   +1 more source

Impact of incomplete percutaneous revascularization in patients With multivessel coronary artery disease: a systematic review and meta-analysis [PDF]

, 2016
Background: Up to half of patients undergoing percutaneous coronary intervention have multivessel coronary artery disease (MVD) with conflicting data regarding optimal revascularization strategy in such patients.
Bagur, Rodrigo, Berry, Colin, Curzen, Nick, De Belder, Mark, Kwok, Chun Shing, Large, Adrian, Ludman, Peter, Mamas, Mamas A., Matsukage, Takashi, Nagaraja, Vinayak, Nolan, James, Ooi, Sze-Yuan, Yoshimachi, Fuminobu   +12 more
core   +2 more sources

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Hemodynamic Evaluation of Coronary Artery Lesions after Kawasaki Disease: Comparison of Fractional Flow Reserve during Cardiac Catheterization with Myocardial Flow Reserve during ¹³N-Ammonia PET

Journal of Cardiovascular Development and Disease
Coronary artery lesions (CALs) after Kawasaki disease present complex coronary hemodynamics. We investigated the relationship between coronary fractional flow reserve (FFR), myocardial flow reserve (MFR), and myocardial blood flow volume fraction (MBF ...
Makoto Watanabe, Ryuji Fukazawa, Tomonari Kiriyama, Shogo Imai, Ryosuke Matsui, Kanae Shimada, Yoshiaki Hashimoto, Koji Hashimoto, Masanori Abe, Mitsuhiro Kamisago, Yasuhiko Itoh   +10 more
doaj   +1 more source

Lifetime cardiovascular management of patients with previous Kawasaki disease. [PDF]

, 2020
Kawasaki disease (KD) is an inflammatory disorder of young children, associated with vasculitis of the coronary arteries with subsequent aneurysm formation in up to one-third of untreated patients.
Brogan, Paul, Burns, Jane C, Cornish, Jacqueline, Diwakar, Vinod, Eleftheriou, Despina, Gordon, John B, Gray, Huon Hamilton, Johnson, Thomas William, Kawasaki Disease Writing Group, on behalf of the Royal College of Paediatrics and Child Health, and the British Cardiovascular Society, Levin, Michael, MacCarthy, Philip, Malik, Iqbal, McCormack, Rachael, Miller, Owen, Tulloh, Robert MR   +14 more
core   +1 more source

Beam hardening artifact reduction using dual energy computed tomography: implications for myocardial perfusion studies [PDF]

, 2015
Background: Myocardial perfusion computed tomography (CTP) using conventional single energy (SE) imaging is influenced by the presence of beam hardening artifacts (BHA), occasionally resembling perfusion defects and commonly observed at the left ...
Capunay, Carlos, Carrascosa, Patricia, Cipriano, Silvia, Cury, Ricardo C., De Zan, Macarena, Deviggiano, Alejandro, Rodriguez Granillo, Gaston Alfredo   +6 more
core   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

The Value of Optical Coherence Tomography Parameters in Estimating Non-Critical Lesions in Patients with Acute Myocardial Infarction

Journal of Cardiovascular Emergencies
Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide. Accurate assessment of coronary lesion severity is essential for guiding revascularization.
Dragoescu Bogdan, Stan Liviu, Ploscaru Vlad, Calmac Lucian, Mihai Cosmin, Marinescu Mugur, Fotea Nicoleta Popa, Tonu Daniel, Dumitru Alexandra, Stanciulescu Diana, Scafa-Udriste Alexandru   +10 more
doaj   +1 more source

Early Outcomes After Total Arch Replacement With Frozen Elephant Trunk in Elderly Patients With Acute Type A Aortic Dissection

AGING MEDICINE, EarlyView.
Across seven centers (2015–2023), we studied 1634 ATAAD patients undergoing TAR+FET and, after propensity matching (n = 699), compared elderly (≥ 60) versus non‐elderly (< 60) outcomes. Elderly patients had higher 30‐day mortality and complications (log‐rank p = 0.002), supporting individualized hybrid strategies, organ‐protective perioperative care ...
Jiajun Liang, Yuan Xue, Yeting Lou, Hao Han, Xiaohan Zhong, Zhou Liu, Tianxu Han, Meili Wang, Wenjian Jiang, Hongjia Zhang, Haiyang Li, Yuanfei Zhao   +11 more
wiley   +1 more source