Results 81 to 90 of about 3,896,573 (293)

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source

TRPC3‐Driven Calcium Microdomains Instruct Peripheral Nerve Regeneration With Protective Implications for Central Neurons

Advanced Science, EarlyView.
How localized Ca2+ signals orchestrate neural repair remains unclear. Here, we show that TRPC3‐driven calcium microdomains direct nerve repair by coupling spatially confined Ca2+ signals to axon regeneration. This module operates in injured peripheral neurons and correlates with neuroprotection in Parkinson's disease, revealing a spatial logic for ...
Yu Lu, Jianbo Zhao, Zhenli Xie, Yuan Wang, Ruolin Wang, Bianbian Wang, Chuhan Shen, Yali Chen, Jingyu Yao, Ziyang Li, Huadong Xu, Zuying Chai, Zhuoyu Zhang, Changhe Wang, Rong Huang   +14 more
wiley   +1 more source

Clinical usefulness of instantaneous wave-free ratio for the evaluation of coronary artery lesion with prior myocardial infarction: A multi-center study

International Journal of Cardiology: Heart & Vasculature, 2020
Background: Fractional flow reserve (FFR) is useful for assessing the functional significance of coronary artery stenosis, even in lesions with prior myocardial infarction (pMI).
Shusuke Fukuoka, Tairo Kurita, Akihiro Takasaki, Tomoyuki Nakata, Naoki Fujimoto, Jun Masuda, Kozo Hoshino, Takashi Tanigawa, Sukenari Koyabu, Masaaki Ito, Kaoru Dohi   +10 more
doaj   +1 more source

Prognostic Value of Fractional Flow Reserve Measured Immediately After Drug-Eluting Stent Implantation [PDF]

, 2017
The predictive value of fractional flow reserve (FFR) measured immediately after percutaneous coronary intervention (PCI) with drug-eluting stent placement has not been prospectively investigated.
Fearon, William F, Jüni, Peter, Tonino, Pim A.L., Toth, Gabor, Pijls, Nico H J, Soheila Aghlmandi, Toth, Gabor G, Tonino, Pim A L, Pijls, Nico H.J., Fearon, William, Piroth, Zsolt, Toth, Gabor G., Bernard De Bruyne, William F. Fearon, Zsolt Piroth, Gabor G. Toth, Peter Jüni, Tonino, PAL (Pim), Nick Curzen, Barbato, E, Aghlmandi, Soheila, Curzen, N Nick, Curzen, Nick, Nico H.J. Pijls, Pijls, NHJ Nico, Bruyne, Bernard De, De Bruyne, Bernard, Barbato, Emanuele, Rioufol, Gilles, Pim A.L. Tonino, Fearon, William F., Emanuele Barbato, Gilles Rioufol   +32 more
core   +2 more sources

Mesoporous‐Shell Monolayer Plasmonic Architecture Enables Quantitative and Decision‐Guided SERS

Advanced Science, EarlyView.
Mesoporous‐shell‐regulated molecular transport combined with monolayer hotspot determinism transforms surface‐enhanced Raman spectroscopy (SERS) from ultrasensitive detection into quantitative and decision‐guided molecular sensing. ABSTRACT Quantitative surface‐enhanced Raman spectroscopy (SERS) has long been impeded by stochastic hotspot formation ...
Guangyao Huang, Ying Wang, Yue Fang, Jingyuan Shao, Sensen Hao, Mancun Zhao, Yuan Yao, Junping Wang, Wei Zhou, Hongzhi Wang   +9 more
wiley   +1 more source

Combined Assessment of Stress Myocardial Perfusion Cardiovascular Magnetic Resonance and Flow Measurement in the Coronary Sinus Improves Prediction of Functionally Significant Coronary Stenosis Determined by Fractional Flow Reserve in Multivessel Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundRecent studies using stress‐rest perfusion cardiovascular magnetic resonance (CMR) demonstrated a close correlation between myocardial ischemia and reduced fractional flow reserve (FFR).
Shiro Nakamori, Hajime Sakuma, Kaoru Dohi, Masaki Ishida, Takashi Tanigawa, Akimasa Yamada, Shinichi Takase, Hiroshi Nakajima, Toshiki Sawai, Jun Masuda, Motonori Nagata, Yasutaka Ichikawa, Kakuya Kitagawa, Eitaro Fujii, Norikazu Yamada, Masaaki Ito   +15 more
doaj   +1 more source

Designing Tissue Function Through Embedded Bioprinting Architectures

Advanced Science, EarlyView.
Embedded bioprinting enables soft, cell‐dense constructs to be fabricated within supporting bath environments. This review introduces a function‐guided framework linking target tissue functions to architectural requirements, supporting bath selection, bioink design, printing dynamics, and validation assays.
Qi Li, Yifei Cao, Jiaxin Lin, Huayong Yang, Hongzhao Zhou   +4 more
wiley   +1 more source

Cardiac Magnetic Resonance for Evaluating Nonculprit Lesions After Myocardial Infarction: Comparison With Fractional Flow Reserve [PDF]

, 2020
Objectives: This study sought to determine the agreement between cardiac magnetic resonance (CMR) imaging and invasive measurements of fractional flow reserve (FFR) in the evaluation of nonculprit lesions after ST-segment elevation myocardial infarction (
van Rossum, AC, Nijveldt, R, Geest, R.J. van der, van der Hoeven, Nina W., Everaars, H., van der Hoeven, NW, Leeuwen, M.A. van, van Leeuwen, Maarten A., Schumacher, S.P., van Rossum, Albert C., Hofman, MBM, Gotte, MJW, van Leeuwen, M.A., Schumacher, Stefan P., Loon, R.B. van, Ven, P.M. van de, Everaars, H, Gotte, M.J., Hofman, Mark B. M., Royen, N. van, van der Geest, Rob J., van de Ven, PM, Nijveldt, R., Gotte, Marco J., van Loon, RB, Janssens, Gladys N., van Loon, Ramon B., van Royen, N, Everaars, Henk, Hofman, M.B.M., Demirkiran, A., Rossum, A.C. van, van de Ven, Peter M., van Royen, Niels, Nijveldt, Robin, Hoeven, N.W. van der, Janssens, G.N., Demirkiran, A, Schumacher, SP, Demirkiran, Ahmet   +39 more
core   +1 more source

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

Efficacy and safety outcomes of fractional flow reserve in guiding clinical therapy of non-ST-segment elevation myocardial infarction compared with angiography alone in elderly Chinese patients

, 2016
Zhao Zhang,* Ke Li,* Jinwen Tian Department of Cardiology, Chinese People’s Liberation Army General Hospital and Hainan Branch, Sanya, People’s Republic of China *These authors contributed equally to this work Objective: Fractional ...
Tian J, Zhang Z, Li K
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