Results 81 to 90 of about 26,752 (329)

Prognostic value of CT myocardial perfusion imaging and CT-derived fractional flow reserve for major adverse cardiac events in patients with coronary artery disease.

Journal of cardiovascular computed tomography, 2019
OBJECTIVES The purpose of this study was to analyze the prognostic value of dynamic CT perfusion imaging (CTP) and CT derived fractional flow reserve (CT-FFR) for major adverse cardiac events (MACE).
M. Assen, M. Assen, C. N. Cecco, Marwen Eid, P. V. K. Doeberitz, M. Scarabello, Francesco Lavra, Maximilian J Bauer, Domenico Mastrodicasa, Taylor M. Duguay, B. Zaki, Gladys G. Lo, Y. Choe, Y. N. Wang, P. Sahbaee, C. Tesche, M. Oudkerk, R. Vliegenthart, R. Vliegenthart, U. J. Schoepf   +19 more
semanticscholar   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

The relationship between Myocardial SPECT and Fractional Flow Reserve: Is it drifting apart? [PDF]

The International Journal of Cardiovascular Imaging, 2009
In the paper, Tc-99 m sestamibi single photon emission computed tomography for guiding percutaneous coronary intervention in patients with multivessel disease: a comparison with quantitative coronary angiography and fractional flow reserve by Forster et.al.
openaire   +2 more sources

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

Computational Analysis of Hemodynamic Indices in Multivessel Coronary Artery Disease in the Presence of Myocardial Perfusion Dysfunction

Computation
Coronary artery disease (CAD) is one of the main causes of death in the world. Functional indices such as fractional flow reserve (FFR), coronary flow reserve (CFR) and instantaneous wave-free ratio (iFR) are used to estimate the severity of CAD ...
Timur Gamilov, Alexander Danilov, Peter Chomakhidze, Philipp Kopylov, Sergey Simakov   +4 more
doaj   +1 more source

Functional assessment of coronary artery disease by intravascular ultrasound and computational fluid dynamics simulation

Revista Portuguesa de Cardiologia, 2014
Clinical trials have shown that functional assessment of coronary stenosis by fractional flow reserve (FFR) improves clinical outcomes. Intravascular ultrasound (IVUS) complements conventional angiography, and is a powerful tool to assess atherosclerotic
Sebastián Carrizo, Xinzhou Xie, Rafael Peinado-Peinado, Angel Sánchez-Recalde, Santiago Jiménez-Valero, Guillermo Galeote-Garcia, Raúl Moreno   +6 more
doaj   +1 more source

The Role of Fractional Flow Reserve in Interventional Treatment of Multivessel Coronary Artery Disease

Український журнал серцево-судинної хірургії, 2022
Selective coronary angiography (CAG) is an invasive diagnostic method for the assessment of the internal lumen and anatomical features of the coronary artery.
Andrii Yu. Gavrylyshyn
doaj   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Fractional Flow Reserve–Guided PCI for Stable Coronary Artery Disease [PDF]

, 2014
Background We hypothesized that in patients with stable coronary artery disease and stenosis, percutaneous coronary intervention (PCI) performed on the basis of the fractional flow reserve (FFR) would be superior to medical therapy.
Mobius-Winckler, Sven,, Manoharan, Ganesh,, Engstrøm, T (Thomas), Oldroyd, Keith, Fearon, William F.,, Witt, Nils,, Curzen, Nick, Pijls, NHJ Nico, Johnson, Jane B.,, Nueesch, E., Pijls, N.H.J., Barbato, E., Maccarthy, P., Limacher, A Andreas, Limacher, Andreas, Rioufol, G., Limacher, A., Piroth, Z., Limacher, Andreas,, Pijls, Nico H J, Johnson, J. B., Barbato, Emanuele,, Piroth, Zsolt, Verlee, Peter,, Kala, Petr, Juni, P., Witt, N., Verlee, P Peter, Nuesch, E., Rioufol, Gilles Gilles, Engstrom, T., Jagic, N Nikola, Witt, Nils Nils, Jueni, Peter,, Rioufol, Gilles,, Mavromatis, K., Verlee, P., Jagic, N., Fearon, W. F., Tonino, Pim, Manoharan, Ganesh, Tonino, P., Engstrøm, T., MacCarthy, Philip,, Jagic, Nikola,, Rioufol, Gilles, Engstroem, Thomas,, Jueni, P., Fearon, William F, Johnson, Jane B, Frobert, O., Mavromatis, Kreton,, Frobert, Ole, Curzen, Nick,, Frøbert, O., Manoharan, G, Kala, Petr Petr, Nueesch, E Eveline, Tonino, PAL (Pim), Barbato, E, Verlee, Peter, Fearon, W.F., Johnson, J.B., Johnson, JB Jane, Bruyne, Bernard De, De Bruyne, Bernard, de Bruyne, B., Kala, Petr,, Barbato, Emanuele, Oldroyd, K., Oldroyd, Keith G, Jueni, P Peter, Mobius-Winckler, S., MacCarthy, PA, De Bruyne, Bernard,, Engström, Thomas, Riouffol, Gilles, Fröbert, Ole,, Mavromatis, K Kreton, Frøbert, O, Piroth, Z Zsolt, Jüni, Peter, MacCarthy, P.A., Nueesch, Eveline,, Manoharan, G., Oldroyd, Keith,, Piroth, Zsolt,, Nüesch, Eveline, Kala, P., Witt, Nils, Pijls, Nico H. J.,, Tonino, Pim,, Curzen, N Nick, Jagic, Nikola, MacCarthy, Philip, Mavromatis, Kreton, Curzen, N., Mobius-Winckler, S Sven, Mobius-Winckler, Sven, Pijls, N. H.   +99 more
core   +1 more source