Results 61 to 70 of about 4,107,542 (294)

Prognostic Implications of Resistive Reserve Ratio in Patients With Coronary Artery Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Resistive reserve ratio is a thermodilution‐based index which integrates both coronary flow and pressure. Resistive reserve ratio represents the vasodilatory capacity of interrogated vessels including both epicardial coronary artery and ...
Seung Hun Lee, Joo Myung Lee, Jonghanne Park, Ki Hong Choi, Doyeon Hwang, Joon‐Hyung Doh, Chang‐Wook Nam, Eun‐Seok Shin, Masahiro Hoshino, Tadashi Murai, Taishi Yonetsu, Hernán Mejía‐Rentería, Tsunekazu Kakuta, Javier Escaned   +13 more
doaj   +1 more source

Medium-term follow-up of intermediate coronary stenoses left unrevascularized based on myocardial fractional flow reserve findings

, 2002
Objective - Coronary stenoses of intermediate severity create difficulties in decision making when revascularization is concerned. Myocardial fractional flow reserve (mFFR), an accurate tool to identify physiological significance of individual coronary ...
Boyaci, B, Ozdemir, M, Dortlemez, O, Dortlemez, H, Timurkaynak, T, Cengel, A, Cemri, M, Yalcin, R   +7 more
core   +1 more source

An investigation into hemodynamically significant coronary artery lesions predictors assessed by fractional flow reserve: A propensity score matching analysis

, 2020
OBJECTIVE: Fractional flow reserve (FFR) provides more useful information regarding myocardial metabolism and demand- supply convenience as compared to anatomical measurements.
Demirelli, Selami, Aksakal, Emrah, GÜLCÜ, Oktay, Kalkan, Kamuran, TOPCU, Selim, Aksu, Ugur   +5 more
core   +1 more source

The value of fractional and coronary flow reserve in predicting myocardial recovery in patients with previous myocardial infarction [PDF]

European Heart Journal, 2008
The aim of the study was to evaluate the relation between fractional flow reserve (FFR) and simultaneously evaluated coronary flow reserve by thermodilution (CFRthermo), with the improvement of left ventricular (LV) function in patients with previous myocardial infarction (MI) undergoing percutaneous coronary intervention (PCI).Study population ...
Branko, Beleslin, Miodrag, Ostojic, Ana, Djordjevic-Dikic, Vladan, Vukcevic, Sinisa, Stojkovic, Milan, Nedeljkovic, Goran, Stankovic, Dejan, Orlic, Natasa, Milic, Jelena, Stepanovic, Vojislav, Giga, Jovica, Saponjski   +11 more
openaire   +2 more sources

A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle

Advanced Science, EarlyView.
This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin, Weiyan Qi, Lifen Lin, Huilin Zheng, Guoxiang Zhao, Quan Chen, Guoqiang Shao, Yifan Wu, Jialiang Hu, Hanmei Xu   +9 more
wiley   +1 more source

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

Accuracy of intravascular ultrasound-derived virtual fractional flow reserve (FFR) and FFR derived from computed tomography for functional assessment of coronary artery disease

BioMedical Engineering OnLine, 2023
Background Coronary computed tomography-derived fractional flow reserve (CT-FFR) and intravascular ultrasound-derived fractional flow reserve (IVUS-FFR) are two functional assessment methods for coronary stenoses.
Wenhao Huang, Jingyuan Zhang, Lin Yang, Yumeng Hu, Xiaochang Leng, Yajun Liu, Hongfeng Jin, Yiming Tang, Jiangting Wang, Xiaowei Liu, Yitao Guo, Chen Ye, Yue Feng, Jianping Xiang, Lijiang Tang, Changqing Du   +15 more
doaj   +1 more source

Macrophage PARP7 Alleviates Septic Cardiomyopathy by Interacting With TBK1 and Suppressing TBK1‐Driven Inflammatory Response

Advanced Science, EarlyView.
In septic cardiomyopathy, PARP7 directly binds TBK1 and mediates its ADP‐ribosylation, thereby repressing TBK1‐driven proinflammatory signaling in macrophages. ABSTRACT Septic cardiomyopathy is a life‐threatening complication of sepsis, and an uncontrolled inflammatory response represents a key pathogenic mechanism. PARP7 negatively regulates the IFN‐I
Jibo Han, Lintao Wang, Xin Zhong, Shenggang Zhao, Huihui Xie, Xue Han, Liming Lin, Yiting Lyu, Ke Xu, Jiajun Xu, Xiaowen Shi   +10 more
wiley   +1 more source

The relationship between Myocardial SPECT and Fractional Flow Reserve: Is it drifting apart? [PDF]

The International Journal of Cardiovascular Imaging, 2009
In the paper, Tc-99 m sestamibi single photon emission computed tomography for guiding percutaneous coronary intervention in patients with multivessel disease: a comparison with quantitative coronary angiography and fractional flow reserve by Forster et.al.
openaire   +2 more sources

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source