Results 61 to 70 of about 19,043 (300)

High‐Resolution and Real‐Time In Situ Generation of Cellular Spheroids by Laser‐Assisted Bioprinting for Guided Microvascularization

Advanced Functional Materials, EarlyView.
Micro‐injection laser‐assisted bioprinting enables ultrafast and precise patterning of small endothelial cell spheroids by injecting a highly concentrated single‐cell suspension into GelMA/ColMA hydrogels. In co‐culture with fibroblasts, controlled pre‐vasculogenic network formation is obtained at microscale resolution.
Charles Handschin, Katharina Wulz, Clotilde Jugie, Marie‐Laure Stachowicz, Shane Fennell, Aurélien Mazet, Malou Lea, Nathalie Dusserre, Jean‐Christophe Fricain, Hugo Oliveira   +9 more
wiley   +1 more source

Collateral donor artery physiology and the influence of a chronic total occlusion on fractional flow reserve [PDF]

, 2015
Background— The presence of a concomitant chronic total coronary occlusion (CTO) and a large collateral contribution might alter the fractional flow reserve (FFR) of an interrogated vessel, rendering the FFR unreliable at predicting ischemia should the ...
Alahmar, A., Alahmar, Albert, Alamgir, F., Alamgir, Farquad, Cunnington, Michael S., Davies, Justin E., Hoye, Angela, Ladwiniec, A., Ladwiniec, Andrew, Mather, Adam N., Nijjer, Sukhjinder S., Oliver, Richard M., Rossington, J., Rossington, Jennifer, Thackray, S., Thackray, Simon   +15 more
core   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

Prognostic Implications of Resistive Reserve Ratio in Patients With Coronary Artery Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Resistive reserve ratio is a thermodilution‐based index which integrates both coronary flow and pressure. Resistive reserve ratio represents the vasodilatory capacity of interrogated vessels including both epicardial coronary artery and ...
Seung Hun Lee, Joo Myung Lee, Jonghanne Park, Ki Hong Choi, Doyeon Hwang, Joon‐Hyung Doh, Chang‐Wook Nam, Eun‐Seok Shin, Masahiro Hoshino, Tadashi Murai, Taishi Yonetsu, Hernán Mejía‐Rentería, Tsunekazu Kakuta, Javier Escaned   +13 more
doaj   +1 more source

The Impact of Myocardial Bridging on Fractional Flow Reserve

, 2022
Arterial stenosis is a problem of immediate significance, as cardiovascular disease is the number one leading cause of death worldwide. Fractional flow reserve (FFR) was proposed to evaluate the functional severity of coronary plaque-induced stenosis more accurately. FFR relies on invasive pressure measurements, while computational fluid dynamics (CFD)
openaire   +2 more sources

Rationale and design of the Clinical Evaluation of Magnetic Resonance Imaging in Coronary heart disease 2 trial (CE-MARC 2): a prospective, multicenter, randomized trial of diagnostic strategies in suspected coronary heart disease [PDF]

, 2015
Background: A number of investigative strategies exist for the diagnosis of coronary heart disease (CHD). Despite the widespread availability of noninvasive imaging, invasive angiography is commonly used early in the diagnostic pathway.
Berry, Colin, Bijsterveld, Petra, Brown, Julia, Everett, Colin C., Greenwood, John P., McCann, Gerry P., Plein, Sven, Ripley, David P., Sculpher, Mark, Walker, Simon   +9 more
core   +1 more source

A Personalized, 3D Printed Polymeric Device for the Prevention of Post‐Myocardial Infarction Cardiac Remodeling

Advanced Healthcare Materials, EarlyView.
Myocardial infarction often leads to pathological remodelling and ventricular dilatation, key features of HFrEF. This study introduces a personalized, 3D‐printed cardiac restraint device (CARD) printed using rationally designed inks displaying the requested printability and mechanical properties.
Nicola Mansour, Daniel Cohn, Ishita Sarkar, Raja Alamore, Kareem Abd Rbo, Offer Amir, Dean Nachman   +6 more
wiley   +1 more source

Accuracy of intravascular ultrasound-derived virtual fractional flow reserve (FFR) and FFR derived from computed tomography for functional assessment of coronary artery disease

BioMedical Engineering OnLine, 2023
Background Coronary computed tomography-derived fractional flow reserve (CT-FFR) and intravascular ultrasound-derived fractional flow reserve (IVUS-FFR) are two functional assessment methods for coronary stenoses.
Wenhao Huang, Jingyuan Zhang, Lin Yang, Yumeng Hu, Xiaochang Leng, Yajun Liu, Hongfeng Jin, Yiming Tang, Jiangting Wang, Xiaowei Liu, Yitao Guo, Chen Ye, Yue Feng, Jianping Xiang, Lijiang Tang, Changqing Du   +15 more
doaj   +1 more source

Effect of Plaque Burden and Morphology on Myocardial Blood Flow and Fractional Flow Reserve

Journal of the American College of Cardiology, 2018
Atherosclerotic plaque characteristics may affect downstream myocardial perfusion, as well as coronary lesion severity.This study sought to evaluate the association between quantitative plaque burden and plaque morphology obtained using coronary computed tomography angiography (CTA) and quantitative myocardial perfusion obtained using [15O]H2O positron
Driessen, R.S., Stuijfzand, W.J., Raijmakers, P.G., Danad, I., Min, J.K., Leipsic, J.A., Ahmadi, A., Narula, J., Ven, P.M. van de, Huisman, M.C., Lammertsma, A.A., Rossum, A.C. van, Royen, N. van, Knaapen, P.   +13 more
openaire   +4 more sources

Diabetes does not impact the diagnostic performance of contrast-based fractional flow reserve: insights from the CONTRAST study [PDF]

, 2017
Background: Adenosine-free coronary pressure wire metrics have been proposed to test the functional significance of coronary artery lesions, but it is unexplored whether their diagnostic performance might be altered in patients with diabetes. Methods:
Adjedj, Julien, Barbato, Emanuele, Esposito, Giovanni, Fearon, William, Ferrone, Marco, Gargiulo, Giuseppe, Hennigan, Barry, Jeremias, Allen, Johnson, Nils, Matsumura, Mitsuaki, On behalf of the CONTRST Study Investigators, Stabile, Eugenio, Trimarco, Bruno, Zimmermann, Frederik   +13 more
core   +2 more sources