Results 61 to 70 of about 8,717 (246)

Quantitative Flow Ratio to Predict Nontarget Vessel–Related Events at 5 Years in Patients With ST‐Segment–Elevation Myocardial Infarction Undergoing Angiography‐Guided Revascularization

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background In ST‐segment–elevation myocardial infarction, angiography‐based complete revascularization is superior to culprit‐lesion‐only percutaneous coronary intervention.
Sarah Bär, Raminta Kavaliauskaite, Yasushi Ueki, Tatsuhiko Otsuka, Henning Kelbæk, Thomas Engstrøm, Andreas Baumbach, Marco Roffi, Clemens von Birgelen, Miodrag Ostojic, Giovanni Pedrazzini, Ran Kornowski, David Tüller, Vladan Vukcevic, Michael Magro, Sylvain Losdat, Stephan Windecker, Lorenz Räber   +17 more
doaj   +1 more source

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

Diagnostic Accuracy of Diastolic Fractional Flow Reserve for Functional Evaluation of Coronary Stenosis

JACC: Asia, 2021
Background: In the resting conditions, narrowing the window of coronary pressure measurements from the whole cardiac cycle to diastole improves diagnostic performance of coronary pressure–derived physiological index. However, whether this also applies to
Yasutsugu Shiono, MD, Hitoshi Matsuo, MD, Hiroshi Fujita, MD, Nobuhiro Tanaka, MD, Yasuo Ogasawara, PhD, Itta Kawamura, MD, Yosuke Katayama, MD, Akiko Matsuo, MD, Yoshiaki Kawase, MD, Tsunekazu Kakuta, MD, Hiroaki Takashima, MD, Hiroyoshi Yokoi, MD, Hiroshi Ohira, MD, Satoru Suwa, MD, Mitsutoshi Oguri, MD, Fumi Yamamoto, MD, Takashi Kubo, MD, Takashi Akasaka, MD, Y. Shiono, Y. Katayama, K. Hironori, T. Kubo, T. Akasaka, N. Tanaka, J. Yamashita, H. Fujita, A. Matsuo, H. Matsuo, Y. Kawase, I. Kawamura, T. Kakuta, M. Hoshino, T. Sugano, H. Takashima, T. Amano, H. Yokoi, Y. Yamamoto, Y. Nozaki, M. Machida, M. Kobori, T. Kikuchi, H. Ohira, H. Yoshino, H. Ishiguro, Y. Wakabayashi, T. Kondo, H. Terai, T. Suwa, T. Kimura, T. Kawajiri, A. Hirohata, S. Uemura, Y. Neishi, T. Sakamoto, M. Yamada, K. Okeie, K. Hishikari, M. Oguri, T. Uetani, T. Saegusa, F. Yamamoto, M. Yamada   +61 more
doaj  

Assessment of myocardial bridge by fractional flow reserve and optical coherence tomography in acute myocardial infarction

IHJ Cardiovascular Case Reports, 2017
Rajesh Vijayvergiya, Ganesh Kasinadhuni, Darshan Krishnappa, Ankush Gupta   +3 more
doaj   +3 more sources

Objective Identification of Intermediate Lesions Inducing Myocardial Ischemia Using Sequential Intracoronary Pressure and Flow Measurements

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Although ischemic heart disease has a complex and multilevel origin, the diagnostic approach is mainly focused on focal obstructive disease as assessed by pressure‐derived indexes.
Valérie E. Stegehuis, Gilbert W. M. Wijntjens, Sukhjinder S. Nijjer, Guus A. de Waard, Tim P. van de Hoef, Sayan Sen, Ricardo Petraco, Mauro Echavarría‐Pinto, Martijn Meuwissen, Ibrahim Danad, Paul Knaapen, Javier Escaned, Justin E. Davies, Niels van Royen, Jan J. Piek   +14 more
doaj   +1 more source

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Data on the impact of scan quality on the diagnostic performance of CCTA, SPECT, and PET for diagnosing myocardial ischemia defined by fractional flow reserve on a per vessel level

Data in Brief, 2019
Scan quality directly impacts the diagnostic performance of non-invasive imaging modalities as reported in a substudy of the PACIFC-trial: “Impact of Scan Quality on the Diagnostic Performance of CCTA, SPECT, and PET for Diagnosing Myocardial Ischemia ...
P.A. van Diemen, R.S. Driessen, W.J. Stuijfzand, P.G. Raijmakers, S.P. Schumacher, M.J. Bom, H. Everaars, J.K. Min, J.A. Leipsic, J. Knuuti, S.R. Underwood, P.M. van de Ven, A.C. van Rossum, I. Danad, P. Knaapen   +14 more
doaj  

Role of stress in dynamic single-photon emission computed tomography with myocardial perfusion reserve determination in assessing the severity of coronary artery stenosis

Российский кардиологический журнал, 2019
Aim. To assess the role of global and selected scintigraphic scores of myocardial perfusion, blood flow and reserve in the anatomical and functional significance of coronary artery (CA) stenosis.Material and methods.
K. V. Zavadovsky, A. V. Mochula, A. V. Vrublevsky, A. E. Baev, A. N. Maltseva, A. A. Boshchenko   +5 more
doaj   +1 more source

Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations [PDF]

Arquivos Brasileiros de Cardiologia, 2019
Coronary computed tomography angiography (CCTA) has gained a prominent role in the evaluation of coronary artery disease. However, its anatomical nature does not allow the evaluation of the functional repercussion of coronary obstructions.
Tiago Augusto Magalhães, Roberto Caldeira Cury, Rodrigo Julio Cerci, José Rodrigues Parga Filho, Ilan Gottlieb, Marcelo Souto Nacif, Ibraim Masciarelli Pinto, Carlos Eduardo Rochitte, Fabio Vilas-Boas, Paulo R. Schvartzman   +9 more
doaj   +3 more sources

EBBP‐Mediated Integrated Stress Response Attenuates Anthracycline‐Induced Cardiotoxicity by Inhibiting the Ferroptosis of Cardiomyocytes

Advanced Science, EarlyView.
EBBP expression is significantly upregulated in DOX‐treated cardiomyocytes. Mechanistically, EBBP interacts with GRP78 to mediate K63‐linked ubiquitination, thereby attenuating the inhibitory GRP78‐PERK interaction and triggering activation of the PERK‐mediated integrated stress response (ISR).
Zilong Chen, Can Chen, Yichen Wu, Yinxue Xia, Ruijie Luo, Jiangcheng Shu, Long Chen, Zhaohui Wang, Cheng Wang, Kai Huang   +9 more
wiley   +1 more source