Results 91 to 100 of about 55,652 (297)

Sex Differences in Atherosclerotic Coronary Artery Disease Patterns

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Sex differences in coronary artery disease (CAD) have been increasingly recognized, as women present with distinct clinical characteristics and outcomes compared with men.
Kazumasa Ikeda   +43 more
doaj   +1 more source

Fractional Flow Reserve: Patient Selection and Perspectives

open access: yesVascular Health and Risk Management, 2021
Joyce Peper,1,2,* Leonie M Becker,1,2,* Jan-Peter van Kuijk,1 Tim Leiner,2 Martin J Swaans1 1Department of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands; 2Department of Radiology, University Medical Center Utrecht, Utrecht, The ...
Peper J   +4 more
doaj  

Implementation of ultrasonic sensing for high resolution measurement of binary gas mixture fractions [PDF]

open access: yes, 2014
We describe an ultrasonic instrument for continuous real-time analysis of the fractional mixture of a binary gas system. The instrument is particularly well suited to measurement of leaks of a high molecular weight gas into a system that is nominally ...
Bates, Richard   +33 more
core   +2 more sources

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Fast Virtual Fractional Flow Reserve Based Upon Steady-State Computational Fluid Dynamics Analysis

open access: yesJACC: Basic to Translational Science, 2017
Fractional flow reserve (FFR)-guided percutaneous intervention is superior to standard assessment but remains underused. The authors have developed a novel “pseudotransient” analysis protocol for computing virtual fractional flow reserve (vFFR) based ...
Paul D. Morris, PhD   +8 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Intravascular Imaging Findings After PCI in Patients With Focal and Diffuse Coronary Artery Disease

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Following percutaneous coronary intervention (PCI), optical coherence tomography provides prognosis information. The pullback pressure gradient is a novel index that discriminates focal from diffuse coronary artery disease based on fractional ...
Hirofumi Ohashi   +16 more
doaj   +1 more source

Coronary flow reserve and microcirculatory resistance in patients with coronary tortuosity and without atherosclerosis

open access: yesJournal of International Medical Research, 2020
Objective Coronary tortuosity may affect epicardial coronary arterial blood flow. This study aimed to investigate the effect of coronary tortuosity on coronary flow reserve and the coronary microcirculation in patients without apparent coronary ...
Yang Li   +3 more
doaj   +1 more source

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