Results 111 to 120 of about 301,214 (427)

Fractional Flow Reserve following Percutaneous Coronary Intervention

Journal of Interventional Cardiology, 2020
Fractional flow reserve (FFR) is routinely used to determine lesion severity prior to percutaneous coronary intervention (PCI). However, there is an increasing recognition that FFR may also be useful following PCI to identify mechanisms leading to ...
Udit Thakur, Nancy Khav, Andrea Comella, Michael Michail, Abdul R. Ihdayhid, Eric Poon, Stephen J. Nicholls, Brian Ko, Adam J. Brown   +8 more
doaj   +1 more source

Nonlinear reserving and multiple contract modifications in life insurance [PDF]

Insurance: Mathematics and Economics 93, July 2020, 187-195, 2019
Life insurance cash flows become reserve dependent when contract conditions are modified during the contract term on condition that actuarial equivalence is maintained. As a result, insurance cash flows and prospective reserves depend on each other in a circular way, and it is a non-trivial problem to solve that circularity and make cash flows and ...
arxiv   +1 more source

Morphology of coronary artery lesions assessed by virtual histology intravascular ultrasound tissue characterization and fractional flow reserve [PDF]

, 2012
Fractional flow reserve (FFR) is an index of the physiological significance of a coronary stenosis. Patients who have lesions with a FFR of >0.80, even optimally treated with medication, have however a MACE rate ranging from 8 to 21%. Coronary plaques at
Alfonso, F. (Fernando), Brugaletta, S. (Salvatore), Bruyne, B. (Bernard) de, Diletti, R. (Roberto), Garcia-Garcia, H.M. (Hector), Gomez-Lara, J. (Josep), Gonzalo, N. (Nieves), Sarno, G. (Giovanna), Serruys, P.W.J.C. (Patrick), Shen, Z.J. (Zhu Jun), Wijns, W. (William)   +10 more
core   +2 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Influence of contrast media dose and osmolality on the diagnostic performance of contrast fractional flow reserve [PDF]

, 2017
Background—Contrast fractional flow reserve (cFFR) is a method for assessing functional significance of coronary stenoses, which is more accurate than resting indices and does not require adenosine.
Berry, Colin, Choi, Dong-Hyun, De Bruyne, Bernard, Fearon, William F., Gould, K. Lance, Jeremias, Allen, Johnson, Nils P., Kobayashi, Yuhei, Nishi, Takeshi, Oldroyd, Keith G., Pijls, Nico H.J.   +10 more
core   +1 more source

FRACTIONAL FLOW RESERVE (FFR)

, 2015
FFR is a form of coronary artery measurement that provides valuable information about the functional significance of coronary artery blockade. It works on a simple hemodynamic principle that the more severe the blockade, the more would be the pressure drop beyond the blockade.
Mahajan, Neeraj, Kartik Patel
openaire   +2 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Sex Differences in Computed Tomography Coronary Stenosis Severity Versus Flow Impairment and Impact on Revascularization, Clinical Events and Health Care Costs: A FORECAST Substudy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The impact of sex‐related differences in coronary atheroma and flow impairment severity on clinical events and costs remains unclear. Methods and Results This is a secondary analysis of patients with stable coronary artery disease who ...
Lavinia Gabara, Jonathan Hinton, Mohamed Kira, James Shambrook, Ausami Abbas, Sam Wilding, Jonathon A. Leipsic, Pamela S. Douglas, Nick Curzen   +8 more
doaj   +1 more source

The Broad Consequences of Narrow Banking [PDF]

arXiv, 2018
We investigate the macroeconomic consequences of narrow banking in the context of stock-flow consistent models. We begin with an extension of the Goodwin-Keen model incorporating time deposits, government bills, cash, and central bank reserves to the base model with loans and demand deposits and use it to describe a fractional reserve banking system ...
arxiv  

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source