Results 41 to 50 of about 60,780 (302)

Improvement of Fractional Flow Reserve after Percutaneous Coronary Intervention Does Not Necessarily Indicate Increased Coronary Flow

European Cardiology Review, 2019
Coronary flow is expected to increase by epicardial lesion modification after successful percutaneous coronary intervention (PCI) in stable angina. According to the concept of fractional flow reserve (FFR), the improvement in FFR after PCI reflects the ...
Rikuta Hamaya, Yoshihisa Kanaji, Eisuke Usui, Masahiro Hoshino, Tadashi Murai, Taishi Yonetsu, Tsunekazu Kakuta   +6 more
doaj   +1 more source

Three-Dimensional Angiographic Characteristics versus Functional Stenosis Severity in Fractional and Coronary Flow Reserve Discordance: A DEFINE FLOW Sub Study

Diagnostics, 2022
Background: Coronary angiography alone is insufficient to identify lesions associated with myocardial ischemia that may benefit from revascularization.
Valerie Stegehuis, Jelmer Westra, Coen Boerhout, Martin Sejr-Hansen, Ashkan Eftekhari, Hernan Mejía-Renteria, Maribel Cambero-Madera, Niels Van Royen, Hitoshi Matsuo, Masafumi Nakayama, Maria Siebes, Evald Høj Christiansen, Tim Van de Hoef, Jan Piek   +13 more
doaj   +1 more source

Microvascular dysfunction in the immediate aftermath of chronic total coronary occlusion recanalization [PDF]

, 2016
Objectives The aim of this study was to compare microvascular resistance under both baseline and hyperemic conditions immediately after percutaneous coronary intervention (PCI) of a chronic total occlusion (CTO) with an unobstructed reference vessel in ...
Alamgir, Farquad, Cunnington, Michael S., Hoye, Angela, Ladwiniec, Andrew, Rossington, Jennifer, Thackray, Simon   +5 more
core   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Capabilities of Modern Semiconductor Gamma Cameras in Radionuclide Diagnosis of Coronary Artery Disease

Diagnostics, 2021
This paper presents a review of the literature concerning the clinical application of modern semiconductor (CZT) gamma cameras in the radioinuclide diagnosis of coronary artery disease.
Michał Błaszczyk, Zbigniew Adamczewski, Anna Płachcińska   +2 more
doaj   +1 more source

The haemodynamic effects of collateral donation to a chronic total occlusion : implications for patient management [PDF]

, 2015
Physiological lesion assessment in the form of Fractional Flow Reserve (FFR) is now well established for the purpose of guiding multi-vessel revascularization.
Hoye, Angela, Ladwiniec, Andrew
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

DIAGNOSTIC ACCURACY OF FFRACTIONAL FLOW RESERVE IN DIAGNOSING STENTABLE INTERMEDIATE STENOSIS IN PATIENTS OF CORONARY ARTERY DISEASE KEEPING ANGIOGRAPHY AS A GOLD STANDARD

Pakistan Armed Forces Medical Journal, 2020
Objective: To determine diagnostic accuracy of fractional flow reserve in diagnosing stentable intermediate stenosis in patients of coronary artery disease keeping angiography as gold standard. Study Design: Cross sectional validation study.
Abid Saeed, Muhammad Fareed, Abid Sharif, Salma Younas, Fatima Gul   +4 more
doaj  

Dynamics of Myocardial Remodeling Activity Markers in Patients with Myocardial Infarction with Persistent ST-Segment Elevation on the Background of Multivascular Coronary Artery Disease Depending on Diagnostic and Treatment Tactics

Український журнал серцево-судинної хірургії, 2021
In patients with myocardial infarction with stable ST-segment elevation, the gold standard is to perform emergency angiography and stenting of the infarct-dependent artery.
D. Yu. Uzun, K. S. Uzun, V. Lazoryshynets   +2 more
doaj   +1 more source