Results 71 to 80 of about 1,361,829 (303)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

On the weighted fractional integral inequalities for Chebyshev functionals

open access: yesAdvances in Difference Equations, 2021
The goal of this present paper is to study some new inequalities for a class of differentiable functions connected with Chebyshev’s functionals by utilizing a fractional generalized weighted fractional integral involving another function G $\mathcal{G ...
Gauhar Rahman   +4 more
doaj   +1 more source

ON FRACTIONAL VOLTERRA INTEGRODIFFERENTIAL EQUATIONS WITH FRACTIONAL INTEGRABLE IMPULSES

open access: yesMathematical Modelling and Analysis, 2019
We consider a class of nonlinear fractional Volterra integrodifferential equation with fractional integrable impulses and investigate the existence and uniqueness results in the Bielecki’s normed Banach spaces. Further, Bielecki-Ulam type stabilities have been demonstrated on a compact interval. A concrete example is provided to illustrate the outcomes
Sagar Sutar, Kishor D. Kucche
openaire   +6 more sources

On the integral of fractional Poisson processes [PDF]

open access: yesStatistics & Probability Letters, 2013
In this paper we consider the Riemann--Liouville fractional integral $\mathcal{N}^{α,ν}(t)= \frac{1}{Γ(α)} \int_0^t (t-s)^{α-1}N^ν(s) \, \mathrm ds $, where $N^ν(t)$, $t \ge 0$, is a fractional Poisson process of order $ν\in (0,1]$, and $α> 0$. We give the explicit bivariate distribution $\Pr \{N^ν(s)=k, N^ν(t)=r \}$, for $t \ge s$, $r \ge k$, the ...
E. Orsingher, POLITO, Federico
openaire   +4 more sources

Optimal control of fractional systems: a diffusive formulation [PDF]

open access: yes, 2010
Optimal control of fractional linear systems on a finite horizon can be classically formulated using the adjoint system. But the adjoint of a causal fractional integral or derivative operator happens to be an anti-causal operator: hence, the adjoint ...
Matignon, Denis
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Fractionally Integrated COGARCH Processes* [PDF]

open access: yesJournal of Financial Econometrics, 2018
We construct fractionally integrated continuous-time GARCH models, which capture the observed long range dependence of squared volatility in high-frequency data. Since the usual Molchan-Golosov and Mandelbrot-van-Ness fractional kernels lead to problems in the definition of the model, we resort to moderately long memory processes by choosing a ...
Haug, Stephan   +2 more
openaire   +2 more sources

Fractional variational problems with the Riesz-Caputo derivative [PDF]

open access: yes, 2012
In this paper we investigate optimality conditions for fractional variational problems, with a Lagrangian depending on the Riesz-Caputo derivative. First we prove a generalized Euler-Lagrange equation for the case when the interval of integration of the ...
Almeida, R.   +2 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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