Results 71 to 80 of about 1,361,829 (303)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
On the weighted fractional integral inequalities for Chebyshev functionals
The goal of this present paper is to study some new inequalities for a class of differentiable functions connected with Chebyshev’s functionals by utilizing a fractional generalized weighted fractional integral involving another function G $\mathcal{G ...
Gauhar Rahman +4 more
doaj +1 more source
ON FRACTIONAL VOLTERRA INTEGRODIFFERENTIAL EQUATIONS WITH FRACTIONAL INTEGRABLE IMPULSES
We consider a class of nonlinear fractional Volterra integrodifferential equation with fractional integrable impulses and investigate the existence and uniqueness results in the Bielecki’s normed Banach spaces. Further, Bielecki-Ulam type stabilities have been demonstrated on a compact interval. A concrete example is provided to illustrate the outcomes
Sagar Sutar, Kishor D. Kucche
openaire +6 more sources
On the integral of fractional Poisson processes [PDF]
In this paper we consider the Riemann--Liouville fractional integral $\mathcal{N}^{α,ν}(t)= \frac{1}{Γ(α)} \int_0^t (t-s)^{α-1}N^ν(s) \, \mathrm ds $, where $N^ν(t)$, $t \ge 0$, is a fractional Poisson process of order $ν\in (0,1]$, and $α> 0$. We give the explicit bivariate distribution $\Pr \{N^ν(s)=k, N^ν(t)=r \}$, for $t \ge s$, $r \ge k$, the ...
E. Orsingher, POLITO, Federico
openaire +4 more sources
Optimal control of fractional systems: a diffusive formulation [PDF]
Optimal control of fractional linear systems on a finite horizon can be classically formulated using the adjoint system. But the adjoint of a causal fractional integral or derivative operator happens to be an anti-causal operator: hence, the adjoint ...
Matignon, Denis
core
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Fractionally Integrated COGARCH Processes* [PDF]
We construct fractionally integrated continuous-time GARCH models, which capture the observed long range dependence of squared volatility in high-frequency data. Since the usual Molchan-Golosov and Mandelbrot-van-Ness fractional kernels lead to problems in the definition of the model, we resort to moderately long memory processes by choosing a ...
Haug, Stephan +2 more
openaire +2 more sources
Fractional variational problems with the Riesz-Caputo derivative [PDF]
In this paper we investigate optimality conditions for fractional variational problems, with a Lagrangian depending on the Riesz-Caputo derivative. First we prove a generalized Euler-Lagrange equation for the case when the interval of integration of the ...
Almeida, R. +2 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

