On multiplicative conformable fractional integrals: theory and applications
In this paper, we first introduce the multiplicative conformable left and right fractional integrals, followed by the derivation of key properties, such as integrability, boundedness, continuity, and the semi-group property, for the newly defined ...
Hüseyin Budak, Büşra Betül Ergün
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On generalized stochastic fractional integrals and related inequalities
The generalized mean-square fractional integrals ${\mathcal{J}_{\rho ,\lambda ,u+;\omega }^{\sigma }}$ and ${\mathcal{J}_{\rho ,\lambda ,v-;\omega }^{\sigma }}$ of the stochastic process X are introduced.
Hüseyin Budak, Mehmet Zeki Sarikaya
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
New Approaches to Fractal–Fractional Bullen’s Inequalities Through Generalized Convexity
This paper introduces a new identity involving fractal–fractional integrals, which allow us to derive several new Bullen-type inequalities via generalized convexity.
Wedad Saleh +4 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Midpoint-type inequalities via twice-differentiable functions on tempered fractional integrals
In this paper, we obtain an equality involving tempered fractional integrals for twice-differentiable functions. By using this equality, we establish several left Hermite–Hadamard-type inequalities for the case of tempered fractional integrals. Moreover,
Fatih Hezenci, Hüseyin Budak
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Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
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Newton-type Inequalities for Fractional Integrals by Various Function Classes
The authors of the paper examine some Newton-type inequalities for various function classes using Riemann-Liouville fractional integrals. Namely, we establish some Newton-type inequalities for bounded functions by fractional integrals.
Hüseyin Budak +2 more
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This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source

